This inclusive text describes hot melt extrusion for pharmaceutical applications, focusing on the materials used for the preparation of solid dispersions, fundamentals for preparing such systems and novel applications using extrusion technology.

Melt Extrusion in Drug Delivery: Three Decades of Progress.- Twin Screw Extrusion for Pharmaceutical Processes.- Properties and Applications of Polyvinyllactam Polymers.- Properties and Applications of Hypromellose Acetate Succinate (HPMCAS) for Solubility Enhancement Using Melt Extrusion.- Cellulose Ethers for Extrusion Applications.- Properties and Applications of Polyethylene Oxide and Ethylcellulose for Tamper Resistance and Controlled Drug Delivery.- Formulation Development of Amorphous Solid Dispersions Prepared by Melt Extrusion.- Non-Sink In Vitro Dissolution Testing of Amorphous Solid Dispersions.- Manufacture of Pharmaceutically Relevant Materials by Mechanochemistry Using Twin Screw Extrusion.- Melt Extruded Controlled Release Dosage  Forms.- Excipient/API Melt Processing via Injection Molding.- Devices and Implants Prepared Using Hot Melt Extrusion.- Solid Lipid Extrusion.- Formulation, Bioavailability and Manufacturing Process Enhancement: Novel Applications of Melt Extrusion in Enabling Product Development.- Hot Melt Extrusion as a Continuous Pharmaceutical Manufacturing Process.- Hot-Melt Extrusion Process Design Using Process Analytical Technology.- Consistency of Pharmaceutical Products: An FDA Perspective on Hot-melt Extrusion Process.- Melt Extrusion: A Commercial Perception to Practicality.- Future Trends.