This book aims to reveal the underlying neural mechanisms of sleep and anesthesia by employing a range of experimental techniques and applying theoretical models of neural activity that predict the mechanisms related to both states. Of course, these models offer deeper insights if their assumptions and resulting data can be correlated to experimental findings, and it is these correlations that the book focuses on. As the outcome of workshops on anesthesia and sleep at the 2007 and 2009 Computational Neuroscience Conferences in Toronto and Berlin, the chapters lay out key theoretical issues as well as hot contemporary research topics. It also details experimental techniques on various spatial scales, such as fMRIand EEG-experiments on the macroscopic, and single-neuron and LFP measurements on the microscopic scale

Foreword: Computing the mind by Anthony Hudetz.- Preface by Axel Hutt.- 1. Sleep and Anesthesia: A Consideration of States, Traits, and Mechanisms by G. Mashour, University of Michigan.- 2. Modelling sleep and general anaesthesia by J. Sleigh, University of Auckland.- Section 1: Sleep.- 3. Quantitative Modeling of Sleep Dynamics by P. Robinson, University of Sydney.- 4. The fine structure of slow-wave sleep oscillations: from single neurons to large networks by A. Destexhe, CNRS Gif-sur-Yvette Paris.- 5. A population network model of neuronal and neurotransmitter interactions regulating sleep-wake behavior in rodent species by V. Booth, University of Michigan.- 6. Neural correlates of human NREM sleep oscillations by P. Maquet, University of Liege.- Section 2: Anesthesia.- 7. A mesoscopic modelling approach to anaesthetic action on brain electrical activity by D. Liley, Swinburne University of Technology.- 8. Progress in modeling EEG effects of general anesthesia: Biphasic response and hysteresis by A. Steyn-Ross, University of Waikato.- 9. EEG modeling in anesthesia: a new insight into mean-field approach for Delta activity generation.- by Behnam Molaee-Ardekani, University of Rennes.- 10. A neural population model of the bi-phasic EEG-power spectrum during general anaesthesia by A. Hutt, INRIA Nancy.- 11. In vivo-electrophysiology of anesthetic action by B. Rehberg-Kluge,  Charite Humboldt University Berlin