This comprehensive book captures and compiles new and current information on hematologic malignancies. New knowledge of cellular disease processes, molecular pathology, and cytogenetic, epigenetic and genomic changes has influenced the current outlook toward haematological malignancies. This recent and ongoing expansion of knowledge on malignant hematology has not previously been utilized to its full capacity due to its diffuse distribution scattered over the internet and research publications. This book is written by experts from the American and European continent, sharing their current thoughts and knowledge on the pathobiology of malignant haematological diseases of the blood, as well as current treatment strategies and future developments in the area of these haematological diseases.

Part 1: Hematopoiesis.1 Normal and Malignant Hematopoiesis (Bijal D. Shah andKenneth S. Zuckerman).2 The Leukemic Genome (Jonathan C. Strefford and Nicholas CPCross).Part 2: Myeloid Malignancies.3 Myeloproliferative Neoplasms (Ruben A. Mesa and AyalewTefferi).4 CML: Molecular Biology of BCR-Able (Javier I.Pinilla-Ibarz, Eric Padron and Lori Hazlehurst).5 Standard Management of Patients with CML (Chronic MyeloidLeukemia) (Elias Jabbour, Jorge Cortes and HagopKantarjian).6 The Molecular Biology of Acute Myeloid Leukemia (JeraldRadich).7 Acute Myeloid Leukemia (Martin S. Tallman, Ritesh Parajuliand Jessica K. Altman).8 Acute promyelocytic leukemia (APL) (Sylvain Thépot,Lionel Ades and Pierre Fenaux).9 A Pluralistic approach to the study of myelodysplasticsyndromes: Evolving pathology of the Seed via the Soil (NaomiGalili, Raymond Cruz, Jamie Stratton, Jessica Clima, Ghulam SajjadKhan and Azra Raza).10 Myelodysplastic Syndrome: A Review of Current Care(Kenneth H. Shain, Alan F. List and Rami S. Komrokji).11 Supportive Care in Myelodysplastic Syndrome (MDS) (HussainI. Saba, Arshia A. Dangol and Donald C. Doll).Part 3: Lymphoid Malignancies.12 Molecular Biology of Chronic Lymphoproliferative Disorders(Monique A. Hartley and Lubomir Sokol).13 Chronic Lymphocytic Leukemia (Terry Hamblin and AngelaHamblin).14 Acute Lymphoblastic Leukemia (Susan O'Brien, StefanFaderl, Deborah Thomas and Hagop M.Kantarjian).15 Large Granular Lymphocyte Leukemia (Xin Liu and Thomas P.Loughran, Jr.).16 Hairy Cell Leukemia (Kevin T. Kim, Darren S. Sigal andAlan Saven).17 Molecular Basis of B-cell Lymphomas (Elizabeth M. Sagatys,Eduardo M. Sotomayor and Jianguo Tao).18 Non-Hodgkin's Lymphomas (Peter McLaughlin and NathanFowler).19 Hodgkin Lymphoma (Michael Crump).Part 4: Plasma Cell Disorders.20 Multiple Myeloma: Molecular Biology, Diagnosis andTreatment (S. Vincent Rajkumar and Shaji Kumar).21 Waldenström's Macroglobulinemia (Robert A. Kyleand Suzanne Hayman).22 Primary Systemic (AL) Amyloidosis (Efstathios Kastritisand Meletios Athanasios Dimopoulos).Part 5: Bone Marrow Transplantation and Quality ofLife.23 Advances in allogeneic hematopoietic cell transplantation:progress in transplantation technology and disease-specificoutcomes (Joseph Pidala and Claudio Anasetti).24 Quality of Life after the diagnosis of HematologicalMalignancies (Mohamed Sorror).