Multiple Analyses in Clinical Trials
Fundamentals for Investigators
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ISBN-13:
9781441918369
Veröffentl:
2010
Einband:
Paperback
Erscheinungsdatum:
29.11.2010
Seiten:
464
Autor:
Lemuel A. Moyé
Gewicht:
698 g
Format:
235x155x25 mm
Serie:
Statistics for Biology and Health
Sprache:
Englisch
Beschreibung:
Concentrating on the rationale for the analyses, the difficulties posed by their interpretation, easily understood solutions, and useful problem sets, this book will help clinical investigators understand multiple analysis procedures and key issues. It is written for advanced medical students, clinical investigators at all levels, research groups within the pharmaceutical industry, regulators at the local, state, and federal level, and biostatisticians.
Introduction * The Rudiments: Methodologic Roots of Clinical Trial Design * Multiple Analyses and the Random Experiment * The Lure and Complexity of Multiple Analyses *Multiple Analyses and Multiple Endpoints * Introduction to Multiple Dependent Analyses * Multiple Dependent Analyses 2 * Introduction to Composite Endpoints * Multiple Analyses and Composite Endpoints * Introduction to Subgroup Analyses * Subgroups II: Effect Domination and Controversy * Subgroups III: Confirmatory Analyses * Multiple Analyses and Multiple Treatment Arms * Combining Multiple Analyses * Conclusions
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