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Introduction to Macromolecular Binding Equilibria
ISBN-13:
9781420052992
Veröffentl:
2007
Seiten:
272
Autor:
Charles P. Woodbury
eBook Typ:
PDF
eBook Format:
EPUB
Kopierschutz:
2 - DRM Adobe
Sprache:
Englisch
Beschreibung:
This compact, graduate-level text focuses on a key area of biophysical chemistry. Introduction to Macromolecular Binding Equilibria first describes the features of binding sites for small molecules and then presents a discussion of the formulation of binding isotherms for simple mathematical models. The book addresses special problems in describing isotherms for linear polymers and examines the complications of binding cooperativity and thermodynamic linkage interactions among multiple ligands. It highlights important aspects of experimental designs, key aspects of ligand binding to planar arrays of sites, and methods for model-free analysis data used to reveal the binding isotherm.
Binding sites. Binding isotherms. Binding linkage, binding competition, and multiple ligand species. Cooperativity. Binding to lattices of sites. Choosing a method and analyzing the data. Appendix: The sequence-generating function method. Index
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