The indentification of steroid structural features that control particular biological effects is the focus of this book. Steroid geometry plays a critical role in steroid activity; therefore, the results of X-ray crystallographic, NMR spectroscopic, and theoretical studies on structure-activity relationships form an integral part of the book.

1. Steroid Structure and Function from X-Ray Crystallographic Studies W.L. Duax 2. 1H and 13C NMR Spectroscopy of Sterols W.K. Wilson and G.J. Schroepfer, Jr. 3. Theoretical Investigations on Steroid Structure and Quantitative Structure-Activity Relationships M. Bohl 4. Two Approaches to Structure-Activity Relationships in the Field of Sex Steroids and Their Analogs T. Ojasoo, J.C. Dore, J.P. Mornon, and J.P. Raynaud 5. Stilbestrol Estrogens- Molecular/Structural Probes for Understanding Estrogen Action K.S. Korach 6. Aromatase- Mechanism and Inhibition P.A. Cole and C.H. Robinson 7. Structure-Activity Relationships of Glucocorticoids- Importance of the Regulated Gene and Trans-Acting Factors in Determining Glucocorticoid and Antiglucocorticoid Activity S.S. Simons, Jr. 8. Molecular Structure and Biological Activity of Vitamin D Metabolites and Their Analogs N. Ikekawa and S. Ishizuka 9. Molecular Structure and Biological Activity of Brassinolide and Related Brassinosteroids T.Yokota and K. Mori 10. Structure-Activity Relationships of Androgens and Anabolics I. Urbankova, Z. Perina, and O. Hance 11. Structure-Activity Relationships of Steroidal Neuromuscular Blocking Agents Z. Tuba and S. Maho 12. Molecular Biology of Cardiotonic Steroids R. Thomas