This volume is a collection of articles that showcase new research that is emerging from laboratory schools, guided by principles of applied developmental science.

1. Introduction to the Special Issue on University Laboratory Preschools in the 21st Century James Elicker and Nancy Barbour 2. Identifying and Addressing Challenges to Research in University Laboratory Preschools Nancy File 3. Child Development Laboratory Schools as Generators of Knowledge in Early Childhood Education: New Models and Approaches Brent A. McBride, Melissa Groves, Nancy Barbour, Diane Horm, Andrew Stremmel, Martha Lash, Carol Bersani, Cynthia Ratekin, James Moran, James Elicker, and Susan Toussaint 4. Creating a Classroom of Inquiry at the University of California at Berkeley: The Harold E. Jones Child Study Center Barbara Scales, Jane Perry, and Rebecca Tracy 5. How Three Young Toddlers Transition From an Infant to a Toddler Child Care Classroom: Exploring the Influence of Peer Relationships, Teacher Expectations, and Changing Social Contexts Susan L. Recchia and Kamila Dvorakova 6. Preservice Teachers' Emotion-Related Regulation and Cognition: Associations With Teachers' Responses to Children's Emotions in Early Childhood Classrooms Rebecca Anne Swartz and Nancy L. McElwain 7. Using a Logic Model to Evaluate Undergraduate Instruction in a Laboratory Preschool Lisa Monroe and Diane M. Horm 8. Laboratory Schools as Places of Inquiry: A Collaborative Journey for Two Laboratory Schools Kay Cutler, Carol Bersani, Pamela Hutchins, Mary Bowne, Martha Lash, Janice Kroeger, Sue Brokmeier, Lynda Venhuizen, and Felicia Black