There is an increasing need throughout the biomedical sciences fora greater understanding of knowledge-based systems and theirapplication to genomic and proteomic research. This book discussesknowledge-based and statistical approaches, along with applicationsin bioinformatics and systems biology. The text emphasizes theintegration of different methods for analysing and interpretingbiomedical data. This, in turn, can lead to breakthroughbiomolecular discoveries, with applications in personalizedmedicine.Key Features:* Explores the fundamentals and applications of knowledge-basedand statistical approaches in bioinformatics and systemsbiology.* Helps readers to interpret genomic, proteomic, and metabolomicdata in understanding complex biological molecules and theirinteractions.* Provides useful guidance on dealing with large datasets inknowledge bases, a common issue in bioinformatics.* Written by leading international experts in this field.Students, researchers, and industry professionals with abackground in biomedical sciences, mathematics, statistics, orcomputer science will benefit from this book. It will also beuseful for readers worldwide who want to master the application ofbioinformatics to real-world situations and understand biologicalproblems that motivate algorithms.