Over the past two decades the benefits of label-free biosensoranalysis have begun to make an impact in the market, and systemsare beginning to be used as mainstream research tools in many drugdiscovery laboratories.Label-Free Technologies For Drug Discovery summarises thelatest and emerging developments in label-free detection systems,their underlying technology principles and end-user case studiesthat reveal the power and limitations of label-free in all areas ofdrug discovery.Label-free technologies discussed include SPR, NMR,high-throughput mass spectrometry, resonant waveguide plate-basedscreening, transmitted-light imaging, isothermal titrationcalorimetry, optical and impedance cell-based assays and otherbiophysical methods. The technologies are discussed in relation totheir use as screening technologies, high-content technologies, hitfinding and hit validation strategies, mode of action and ADME/T,access to difficult target classes, cell-based receptor/ligandinteractions particularly orphan receptors, and antibody and smallmolecule affinity and kinetic analysis.Label-Free Technologies For Drug Discovery is anessential guide to this emerging class of tools for researchers indrug discovery and development, particularly high-throughputscreening and compound profiling teams, medicinal chemists,structural biologists, assay developers, ADME/T specialists, andothers interested in biomolecular interaction analysis.