A must-have companion for medical students and junior doctors for almost four decades, Lecture Notes: Clinical Pharmacology and Therapeutics provides concise yet thorough coverage of the principles of clinical pharmacology, the major characteristics of therapeutics, and the practical aspects of prescribing drugs to alleviate symptoms and to treat disease.Whether you are preparing for examinations or prescribing to patients, the tenth edition offers readers current and authoritative insight into the essential practical and clinical knowledge. Logically organised chapters allow for rapid location of key information, while examples of commonly encountered scenarios illustrate how and when to use drugs in clinical situations. Throughout the text, practice questions, prescribing guidelines, and self-assessment tests clarify and reinforce the principles that inform appropriate clinical decision-making.* Presents an up-to-date review of drug use acrossall major clinical disciplines* Offers a timely overview of clinical drug trials and development* Provides new clinical scenarios to relate chapter content to real-life application* Contains colour-coded "Key Points" and "Prescribing Points" to highlight important information* Includes chapter introductions and summaries, and numerous figures, tables, and colour illustrationsLecture Notes: Clinical Pharmacology and Therapeutics, Tenth Edition, is an essential resource for medical students, junior doctors, and other prescribers looking for an up-to-date reference on pharmacological principles, prescribing, and therapeutics.

Preface viContributors viiPart 1 Principles of clinical pharmacology1 Pharmacodynamics and pharmacokinetics 32 Clinical trials and drug development 293 Pharmacoeconomics: the economic evaluation of new drugs 354 Practical prescribing 42Part 2 Aspects of prescribing5 Gastrointestinal system 516 Cardiovascular system: Management of coronary artery disease and its complications 637 Respiratory system 1028 Nervous system 1139 Infection 14210 Drugs and endocrine disease 17511 Genitourinary system 19612 Malignant disease 21113 Drugs and the blood 22114 Musculoskeletal system 23615 Immunopharmacology 24216 Travel medicine 25517 Analgesia and anaesthesia 26618 Poisoning and drug overdose 281Index 295