The latest edition of the seminal reference on the care and management of laboratory and research animalsThe newly revised Ninth Edition of The UFAW Handbook on the Care and Management of Laboratory and Other Research Animals delivers an up-to-date and authoritative exploration on worldwide developments, current thinking, and best practices in the field of laboratory animal welfare science and technology.The gold standard in laboratory and captive animal care and management references, this latest edition continues the series' tradition of excellence by including brand-new chapters on ethical review, the care of aged animals, and fresh guidance on the care of mole rats, corvids, zebrafish, and decapods.The book offers introductory chapters covering a variety of areas of laboratory animal use, as well as chapters on the management and care of over 30 different taxa of animals commonly utilised in scientific procedures and research around the world. It also provides:* A thorough introduction to the design of animal experiments, laboratory animal genetics, and the phenotyping of genetically modified mice* Comprehensive explorations of animal welfare assessment and the ethical review process* Practical discussions of legislation and oversight of the conduct of research using animals from a global perspective* In-depth examinations of the planning, design, and construction of efficient animal facilities, special housing arrangements, and nutrition, feeding, and animal welfareThe UFAW Handbook on the Care and Management of Laboratory and Other Research Animals Nineth Edition is essential for laboratory animal scientists, veterinarians, animal care staff, animal care regulatory authorities, legislators, and professionals working in animal welfare non-governmental organizations.

List of contributors viiForeword xi1 Introduction 1Claire Richardson and Huw GolledgePart 1 Implementing the Three Rs in research using animals 32 The Three Rs 5Adrian Smith and Jon Richmond3 The design of animal experiments 23Simon T. Bate and S. Clare Stanford4 An introduction to laboratory animal genetics 40Michelle Stewart and Sara Wells5 Phenotyping of genetically modified mice 54Jan-Bas Prins and Sara Wells6 Brief introduction to welfare assessment: a 'toolbox' of techniques 64Jennifer Lofgren7 Welfare and 'best practice' in field studies of wildlife 84Julie Lane and Robbie A. McDonald8 Legislation and oversight of the conduct of research using animals: a global overview 101Kathryn Bayne, Javier Guillen, Malcolm P. France and Timothy H. Morris9 Planning, design and construction of the modern animal facility 122Ken Applebee, Christopher Sear and Steven Cubitt10 Environmental enrichment: animal welfare and scientific validity 137Hanno Würbel and Janja Novak11 Special housing arrangements 150Mike Dennis12 Transportation of laboratory animals 171Sonja T. Chou, Donna Clemons, Nicolas Dudoignon, Guy Mulder and Aleksandar Popovic13 Nutrition, feeding and animal welfare 191Graham Tobin and Annette Schuhmacher14 Attaining competence in the care of animals used in research 220Bryan Howard and Marcel Gyger15 The use of positive reinforcement training techniques to enhance the care and welfare oflaboratory and research animals 236Gail Laule16 3Rs considerations when using ageing animals in science 251J. Norman Flynn, Linda Horan, Carl S. Tucker, David Robb and Michael J.A. Wilkinson17 Euthanasia and other fates for laboratory animals 268Huw Golledge18 Ethics review of animal research 281I. Anna S. Olsson and Peter SandøeAppendix 294Penny Hawkins and Maggy JenningsPart 2 Species kept in the laboratory 297Mammals 29919 The laboratory opossum 301John L. VandeBerg and Sarah Williams-Blangero20 Tree Shrews 324Eberhard FuchsRodentia and Lagomorpha 34021 The laboratory mouse: Biology, behaviour, enrichment and welfare: first principles and realsolutions for laboratory mice 340Kathleen R. Pritchett-Corning and Joseph P. Garner22 The laboratory rat 379Sietse F. de Boer and Jaap M. Koolhaas23 The laboratory gerbil 400Elke Scheibler24 The Syrian hamster 419Christina Winnicker and K.R. Pritchett-Corning25 Voles 430Petra Kirsch26 The naked mole-rat (Heterocephalus glaber) 442Chris G. FaulkesAppendix A 45927 The guinea pig 465Sylvia Kaiser, Christine Krüger and Norbert Sachser28 The laboratory rabbit 484Lena Lidfors and Therese EdströmCarnivora 50629 The ferret 506Maggie Lloyd30 The laboratory dog 518Laura Scullion Hall and Jackie Boxall31 The domestic cat 546Emma DesforgesUngulates 57032 Pigs and minipigs 570Adrian Zeltner and Henrik Duelund Pedersen33 Cattle 596Ute Weyer and Shellene Hurley34 Sheep and goats 609Colin L. Gilbert and Cathy M. Dwyer35 The Horse 628Heather Ewence and Fleur WhitlockNon-Human Primates 66236 The mouse lemurs 662Jennifer Wittkowski, Annette Klein, Annika Kollikowski, Marina Scheumann, Daniel Schmidtke, Elke Zimmermann and Ute Radespiel37 Marmosets and tamarins 683Hannah M. Buchanan-Smith38 Capuchin monkeys 707James R. Anderson, Elisabetta Visalberghi and Arianna Manciocco39 Old world monkeys 721Jaco Bakker, Annet L. Louwerse, Marit K. Vernes and Jan A.M. LangermansBirds 73940 The domestic fowl 741Ian J.H. Duncan41 The Japanese quail 762Rusty Lansford and Kimberly M. Cheng42 The zebra finch 787Ruedi G. Nager, Michael J.A. Wilkinson and Graham Law43 Pigeons and doves 807Stephen E.G. Lea, Anthony McGregor, Mark Haselgrove and Catriona M.E. Ryan44 The European starling 824Melissa Bateson45 Corvids 839Rachael Miller, Martina Schiestl and Nicola S. ClaytonReptiles and Amphibia 85346 Terrestrial reptiles: lizards, snakes and tortoises 855John E. Cooper47 An amphibian 'laboratory model', Xenopus 881Richard TinsleyFish 90548 Fishes 907Sonia Rey Planellas and Carlos Garcia de Leaniz49 Zebrafish 933Carole WilsonCephalopoda 95750 Cephalopoda 959Meghan Holst, Ryan B. Howard and Robyn J. CrookDecapoda 99151 Decapod crustaceans 993Robert W. Elwood and Ray W. IngleIndex 1012