Stem Cell Nanoengineering reviews the applications of nanotechnology in the fields of stem cells, tissue engineering, and regenerative medicine. Topics addressed include various types of stem cells, underlying principles of nanobiotechnology, the making of nano-scaffolds, nano tissue engineering, applications of nanotechnology in stem cell tracking and molecular imaging, nano-devices, as well as stem cell nano-engineering from bench to bedside.Written by renowned experts in their respective fields, chapters describe and explore a wide variety of topics in stem cell nanoengineering, making the book a valuable resource for both researchers and clinicians in biomedical and bioengineering fields.

About the Editors ixContributors xiPreface xviiPart 1 An Introduction to Stem Cells 11 Adult Stem Cells 3Andreas Nussler and Sahar Olsadat Sajadian2 Pluripotent Stem Cells 25Hossein Azizi, Akbar Hajizadeh Moghaddam, and ThomasSkutella3 Interactions of Stem Cells and Components of the ExtracellularMatrix 35Anna K. Blakney, Julie J. Antetomaso, Winnie W. Leung, andDeok-Ho Kim4 Regenerative Medicine and Cell Therapy: Past, Present, andFuture 47Hooman Sadri-Ardekani and Anthony AtalaPart 2 An Introduction to Nanotechnology 675 Principles of Nanotechnology 69Jerzy Leszczynski6 Stem-Cell Nanoengineering: Explorations in a Rapidly MovingField 87Abhalaxmi Singh and Sanjeeb K. SahooPart 3 Nanostructures for Stem-Cell Engineering -Engineering Approach 977 Nanopatterned Surfaces for Stem-Cell Engineering 99Waleed Ahmed El-Said, Tae-Hyung Kim, Ki-Bum Lee, and Jeong-WooChoi8 Biomimetic Nanostructures by Electrospinning andElectrospraying 123Elham Vatankhah, Molamma P. Prabhakaran, and SeeramRamakrishna9 Nanoparticles for Stem-Cell Engineering 143Esmaiel Jabbari10 Toxicology of Nanobiomaterials 171Shahin Bonakdar and Omid MashinchianPart 4 Control of Stem-Cell Fate by Engineering ofMicroenvironment 18511 Stem-Cell Responses to Surface Nanotopographies 187Peng-Yuan Wang and Wei-Bor Tsai12 Control of Mesenchymal Stem-Cell Fate by Engineering theNanoenvironment 205Habib Nikukar, Stuart Reid, Mathis O. Riehle, Adam S.G. Curtis,and Matthew J. Dalby13 Delivery of Molecules and Genes/Small Interfering RNA intoStem Cells by Nanoengineering 223Mohsen AshjariPart 5 Nanotissue Engineering - Biological Approachalong with Differentiation 24314 Expansion of Stem Cells by Nanotissue Engineering 245Amir Mellati and Hu Zhang15 Nanotissue Engineering of Neural Cells 265Sasan Jalili-Firoozinezhad, Fahimeh Mirakhori, and HosseinBaharvand16 Nanotechnology and Cardiovascular Tissue Engineering285Savneet Kaur and Upasana Rishiraj17 Nanotissue Engineering of Musculoskeletal Cells 299Mohamadreza Baghaban Eslaminejad, Leila Taghiyar, and FatemehSafari18 Nanotissue Engineering of Skin Cells 315Daisy M. Ramos, Aditi Subramanian, Aja Aravamudhan, MatthewHarmon, Roshan James, Namdev B. Shelke, and Sangamesh G.Kumbar19 High-Throughput Screening of Stem Cell Self-Renewal andDifferentiation on Nanomaterials 327Perry T. Yin, Tae-Hyung Kim, Jeong-Woo Choi, and Ki-BumLeePart 6 Nanotechnology in Stem-Cell Imaging 34520 Nanotechnology for Cellular Imaging 347Miroslaw Janowski, P. Walczak, and J.W.M. BultePart 7 Nanotissue Engineering and Clinical Applications36321 Advancing Translational Nanotechnology to ClinicalApplication 365Michelle Griffin, Shima Salmasi, Naghmeh Naderi, Peter E.Butler, and Alexander M. Seifalian22 Stem-Cell Nanoengineering from Bench to Bed 381Omid Mashinchian, Shahin Bonakdar, Shahriar Sharifi, and MortezaMahmoudiIndex 397