Cancer imposes daunting effects on the nervous systemBrain cancer is one of the most devastating diagnoses aphysician can deliver. Cancer of the nervous system can take manydifferent forms. Treatment is specific to the type of malignancy,its location in the nervous system and, increasingly, its molecularcharacteristics. The challenges manifest further when managementchoices need to be made, and multidisciplinary approaches arerequired. Additional complexities arise in children, where thedeveloping neurological system requires more sensitivetreatment.Neuro-oncology unmasks the complexities to provide astraightforward guide to cancers of the nervous system. Following ageneral approach to diagnosis and treatment, the clinical aspectsof specific cancer types in adults and children are explained inpractical terms. A final section considers the effect of systemcancer on the nervous system and the side effects of treatment.Clinical in approach, practical in execution,Neuro-oncology will help you diagnose and manage yourpatients more effectively.Neurology in PracticeSeries EditorsRobert A Gross , MD, PhD, Department of Neurology,University of Rochester Medical Center, Rochester, New York,USAJonathan W Mink, MD, PhD, Department of Neurology,University of Rochester Medical Center, Rochester, New York,USAThe Neurology in Practice series provides clinical 'inthe office' or 'at the bedside' guides to effective patient carefor neurologists. The tone is practical, not academic, with authorsoffering guidance on what might be done and what should be avoided.The books are informed by evidence-based practice and feature:* Algorithms and guidelines where they are appropriate* 'Tips and Tricks' boxes - hints on improvingoutcomes* 'Caution' warning boxes - hints on avoidingcomplications* 'Science Revisited' - quick reminder of the basic scienceprinciples* Summaries of key evidence and suggestions for furtherreading

List of Contributors, xxxForewordPrefaceAcknowledgementsSection I: Overview and General Aspects of Theory1 Diagnosis of Brain Tumors: Clinical and RadiographicIsabel Arrillaga-Romany, Eudocia Quant Lee and Patrick Y.Wen2 Epidemiology and EtiologyMelissa L. Bondy, Yanhong Liu and Michael Scheurer3 General Aspects of SurgeryBrian Williams, Robert Louis and Mark Shaffrey4 General Approach to Radiation OncologyJennifer S. Yu and Daphne Haas-Kogan5 General Aspects of Chemotherapy including "BiologicAgents"Jethro Hu and Santosh KesariSection II: Adult Nervous System Tumors6 Malignant Gliomas in AdulthoodMichael Ivan, Matthew Tate, and Jennifer Clarke7 LGG and Oligodendrogliomas in AdulthoodDerek R Johnson and Kurt A. Jaeckle8 EpendymomasKanwal P.S. Raghav and Mark Gilbert9 Germ Cell Tumors and Other Pineal Region TumorsGeneviève Legault and Jeffrey C. Allen10 Sellar Tumors: Pituitary Adenomas andCraniopharyngiomasRobert G. Louis and Robert Dallapiazza and John Jane Jr.11 MeningiomasWendy Sherman and Jeffrey Raizer12 Intradural Spinal Cord TumorsBen Shofty, Akiva Korn, Zvi Lidar and Shlomi ConstantiniSection III: Pediatric Brain Tumors13 Gliomas in ChildhoodBruce H. Cohen14 Embryonal TumorsRoger J. Packer15 Infantile Brain TumorsAlyssa ReddySection IV: Systemic Concerns to the CNS and TreatmentSequelea16 Primary Central Nervous System LymphomasJerome Graber and Antonio M.P. Omuro17 Intracranial MetastasesMary Welch and Thomas J. Kaley18 Spinal Cord CompressionMelike Mut19 Leptomeningeal MetastasesSean Grimm and Marc Chamberlain20 Immune Mediated Paraneoplastic Neurologic Disorders: AnOverviewMyrna R. Rosenfeld and Josep Dalmau21 Neurotoxicity of Radiation Therapy and ChemotherapyEudocia C. Quant Lee