Structural Bioinformatics was the first major effort to showthe application of the principles and basic knowledge of the largerfield of bioinformatics to questions focusing on macromolecularstructure, such as the prediction of protein structure and howproteins carry out cellular functions, and how the application ofbioinformatics to these life science issues can improve healthcareby accelerating drug discovery and development. Designed primarilyas a reference, the first edition nevertheless saw widespread useas a textbook in graduate and undergraduate university coursesdealing with the theories and associated algorithms, resources, andtools used in the analysis, prediction, and theoreticalunderpinnings of DNA, RNA, and proteins.This new edition contains not only thorough updates of theadvances in structural bioinformatics since publication of thefirst edition, but also features eleven new chapters dealing withfrontier areas of high scientific impact, including: sampling andsearch techniques; use of mass spectrometry; genome functionalannotation; and much more.Offering detailed coverage for practitioners while remainingaccessible to the novice, Structural Bioinformatics, SecondEdition is a valuable resource and an excellent textbook for arange of readers in the bioinformatics and advanced biologyfields.Praise for the previous edition:"This book is a gold mine of fundamental and practicalinformation in an area not previously well represented in bookform."--Biochemistry and Molecular Education"... destined to become a classic reference work for workers atall levels in structural bioinformatics...recommended with greatenthusiasm for educators, researchers, and graduatestudents."--BAMBED"...a useful and timely summary of a rapidly expandingfield."--Nature Structural Biology"...a terrific job in this timely creation of a compilation ofarticles that appropriately addresses this issue."--Briefings in Bioinformatics