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Recent Advancement in Prodrugs
ISBN-13:
9781000057973
Veröffentl:
2020
Seiten:
350
Autor:
Kamal Shah
eBook Typ:
PDF
eBook Format:
EPUB
Kopierschutz:
0 - No protection
Sprache:
Englisch
Beschreibung:
Prodrugs are said to be bioreversible derivatives which on biotransformation change into active pharmacophore. Prodrugs has been extensively studied amongst the drug design scientists for a wide range of applications. This book will cover the specific examples of prodrugs that overcomes drugs side-effects.
Recent advancements in New drug design and development of prodrugs. Codrugs: Optimum use through prodrugs. Role of Prodrugs in Drug Design. Prodrugs for enhancement of lipophilicity. Lipidic Prodrugs for Drug Delivery: Opportunities and Challenges. The progress of prodrugs in drug solubility. Prodrugs for CNS drug delivery. Prodrugs for Cancer Treatment. Prodrugs in cancer nanomedicine and therapy. Nitroreductases in prodrug therapies. Prodrug approach using carboxylesterase: Different substrate specificities of human carboxylesterase isozymes. Mathematical models for ADME of prodrugs. Prodrug Approaches for Natural Products. Biotechnology based prodrug approach for cell-specific targeting: its theoretical basis and application.
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