Surface plasmon resonance (SPR) plays a dominant role in real-time interaction sensing of biomolecular binding events. Although the last decades have seen the birth of various books on sensors and biosensors with some mention of surface plasmon resonance, such a comprehensive work on SPR covering the issues relevant for the interested student or the practicing researcher has long been awaited. The Handbook of Surface Plasmon Resonance covers all relevant aspects of present technology spanning a bridge between theory, instrumentation and applications. The book provides a thorough theoretical introduction, including kinetic models of biomolecular interactions as well as a practical guide for assay development. The book describes the instrumentation of SPR in terms of optics, fluidics, surface chemistries and kinetics with an easy-to-follow guide of how to use the technique providing relevant applications. The history of SPR, new trends, and a vision of future developments and needs of the SPR market are given. The potential of SPR is revealed by showing highly exciting and unique opportunities for unraveling the functional relationships of complex biological processes. The book is a comprehensive source of information with easy to use, stand-alone chapters, and will be essential for scientists in industry and academia working with or affiliated to the technology. Intended for a wide audience, The Handbook of Surface Plasmon Resonance is also students aspiring to use the technology, and the wide public interested in SPR as a phenomenon and in its applications.

Chapter 1: Introduction to Surface Plasmon Resonance; Chapter 2: Physics of Surface Plasmon Resonance; Chapter 3: SPR Instrumentation; Chapter 4: Kinetic Models Describing Biomolecular Interactions at Surfaces; Chapter 5: Kinetic and Thermodynamic Analysis of Ligand-Receptor Interactions: SPR Applications in Drug Development; Chapter 6: Surface Chemistry in SPR Technology; Chapter 7: Measurement of the Analysis Cycle: Scanning SPR Microarray Imaging of Autoimmune Diseases; Chapter 8: Advanced Methods for SPR Imaging Biosensing; Chapter 9: Surface Plasmon Fluorescence Techniques for Bioaffinity Studies; Chapter 10: SPR Imaging for Clinical Diagnostics; Chapter 11: The Benefits and Scope of Surface Plasmon Resonance-based Biosensors in Food Analysis; Chapter 12: Future Trends in SPR Technology