Discusses treatment strategies for malignant mesothelioma, pulmonary edema, fibrosis, emphysema, and bronchiectasis. This work considers glycosaminoglycans as novel therapeutic agents or targets in lung disease; the role of proteoglycans in determining mechanical behavior of lung tissue; hyaluronan and its receptors in wound healing, and more.

Proteoglycans of the Lung Peter J. RoughleyHyaluronan in Lung Function: An Overview Paul W. NobleMorphological Tools for Studying Lung Proteoglycans Paulo Sampaio Guitierrez and Vera Demarchi AielloProteoglycans, Lung Physiology, and Mechanical StrainMara S. LudwigHyaluronan and Its Receptors in Lung Health and Disease Rashmin C. Savani and Horace M. DelisserHyaluronan and Hyaladherin Signaling in the Lung Sara Hamilton, Eva A. Turley, and Fu-Sheng WangHyaluronan in Malignant MesotheliomaAnders L. Thylen and Gunnar MartenssonMatrix Proteoglycans in Development of Pulmonary Edema Daniela Negrini, Alberto Passi, Giancarlo de Luca, and Giuseppe MiserocchiThe Role of Small Proteoglycans in the Formation of FribrosisGunilla Westergren-Thorsson, Ellen Tufvesson, Erik Eklund, and Anders MalmstromVersican in the Cell Biology of Pulmonary FibrosisClive R. RobertsDecorin in Asthma Anthony E. RedingtonRole of Proteoglycans in the Development and Pathogenesis of EmphysemaYmke M. Van Der Geld, Jeanette F. M. Van Straaten, Dirkje S. Postma, and Wim TimensProteoglycans in Normal and Pathological Bronchial MucusK. Ramakrishnan BhaskarVascular ProteoglycansHannu J el en and Thomas N. WightDegradation of Lung Matrix Proteoglycans in Bronchiectasis Daisy Kwok Yan Shum and Mary Sau Man IpEffect of Hypoxia on Glycosaminoglycan Synthesis by Lung CellsEleni Papakonstantinou and George Karakiulakis and Michael RothIntegrins, Proteoglycans, and Lung DiseaseJiahua XuHeparin as a Potential Therapeutic Agent to Reverse Vascular Remodeling Hari G. Garg, Charles A. Hales, and Robert J. LinhardtAuthor IndexSubject Index