This collection on case-based reasoning in the natural- and human sciences showcases some ways that scholars think with small instances while en route, or not, to more general laws.

Introduction / Angela N.H. Creager, Elizabeth Lunbeck, and M. Norton Wise 1Part 1: BiologyRedesigning the Fruit Fly: The Molecularization of Drosophila / Marcel Weber 23Wormy Logic: Model Organisms as Case-Based Reasoning / Rachel A. Ankeny 46Model Organisms as Powerful Tools for Biomedical Research / E. Jane Albert Hubbard 59The Troop Trope: Baboon Behavior as a Model System in the Postwar Period / Susan Sperling 73Part 2: SimulationsFrom Scaling to Simulation: Changing Meanings and Ambitions of Models in Geology / Naomi Oreskes 93Models and Simulations in Climate Change: Historical, Epistemological, Anthropological, and Political Aspects / Amy Dahan Dalmedico 125The Curios Case of the Prisoner’s Dilemma: Model Situation? Exemplary Narrative? / Mary S. MorganPart 3: Human SciencesThe Psychoanalytic Case: Voyeurism, Ethics, and Epistemology in Robert Stoller’s Sexual Excitement / John Forrester 189“To Exist Is to Have Confidence in One’s Way of Being”: Rituals as Model Systems / Clifford Geertz 212Democratic Athens as an Experimental System: History and the Project of Political Theory / Josiah Ober 225Latitude, Slaves, and the Bible: An Experiment in Microhistory / Carlo Ginzburg 243Afterword: Reflections on Exemplary Narratives, Cases, and Model Organisms / Mary S. Morgan 264Contributors 275Index 279