Where do you begin to look for a recent, authoritative article on the diagnosis or management of a particular malignancy? The few general oncology text­ books are generally out of date. Single papers in specialized journals are informative but seldom comprehensive; these are more often preliminary reports on a very limited number of patients. Certain general journals frequently publish good in-depth reviews of cancer topics, and published symposium lectures are often the best overviews available. Unfortunately, these reviews and supplements appear sporadically, and the reader can never be sure when a topic of special interest will be covered. Cancer Treatment and Research is a series of authoritative volumes that aim to meet this need. It is an attempt to establish a critical mass of oncology literature covering virtually all oncology topics, revised frequently to keep the coverage up to date, and easily available on a single library shelf or by a single personal subscription. We have approached the problem in the following fashion: first, by dividing the oncology literature into specific subdivisions such as lung cancer, geni­ tourinary cancer, pediatric oncology, etc.; and second, by asking eminent authorities in each of these areas to edit a volume on the specific topic on an annual or biannual basis. Each topic and tumor type is covered in a volume appearing frequently and predictably, discussing current diagnosis, staging, markers, all forms of treatment modalities,basic biology, and more.

I. Basic Aspects of Oncogenes in Malignant Transformation.- 1. Oncogenes and proto-oncogenes: General concepts.- 2. Molecular biology: Concepts and techniques.- 3. The myc family of nuclear proto-oncogenes.- 4. The ras family of oncogenes.- 5. src-related protein tyrosine kinases.- 6. The epidermal growth factor receptor and its ligands.- 7. The platelet-derived growth factor system.- 8. Transforming growth factors-? and -? and their potential roles in neoplastic transformation.- II. Clinical Aspects of Oncogenes in Human Neoplasia.- 9. Oncogenes in human solid tumors.- 10. Oncogenes in human leukemias and lymphomas.- 11. Human retrovirus-associated malignancy.- 12. The human DNA tumor viruses: Human papilloma virus and Epstein-Barr virus.- 13. Molecular biology of the human retinoblastoma gene.- 14. Therapeutic applications of oncogenes.