Beschreibung:
Batch Effects and Noise in Microarray Experiments: Sources andSolutions looks at the issue of technical noise and batcheffects in microarray studies and illustrates how to alleviate suchfactors whilst interpreting the relevant biological information.Each chapter focuses on sources of noise and batch effectsbefore starting an experiment, with examples of statistical methodsfor detecting, measuring, and managing batch effects within andacross datasets provided online. Throughout the book the importanceof standardization and the value of standard operating proceduresin the development of genomics biomarkers is emphasized.Key Features:* A thorough introduction to Batch Effects and Noise inMicrorarray Experiments.* A unique compilation of review and research articles onhandling of batch effects and technical and biological noise inmicroarray data.* An extensive overview of current standardizationinitiatives.* All datasets and methods used in the chapters, as well ascolour images, are available on href="the-batch-effect-book.org/">the-batch-effect-book.orgso that the data can be reproduced.An exciting compilation of state-of-the-art review chapters andlatest research results, which will benefit all those involved inthe planning, execution, and analysis of gene expressionstudies.