Multiple Sclerosis and CNS Inflammatory Disorders is a practical guide to effective care of patients with multiple sclerosis and other neuroimmunologic and CNS inflammatory disorders.It provides the scientific basis of multiple sclerosis including etiology, epidemiology, and pathogenesis. It covers the diagnostic process, the course of the disease and prognosis, and the use of MRI in diagnosis and disease monitoring. Disease-modifying treatment algorithms for relapsing-remitting multiple sclerosis, switching therapy, and progressive multiple sclerosis treatment algorithms are all discussed in detail. It also addresses multiple sclerosis in childhood and pregnancy and includes assessment of alternative therapies.This new addition to the Neurology in Practice series contains practical guidance and learning features:* Algorithms and guidelines* "Tips and Tricks" boxes on improving outcomes* "Caution" warning boxes to avoiding problems* "Science Revisited"--quick reminders of the basic science principles necessary for understandingMultiple Sclerosis and CNS Inflammatory Disorders is an ideal reference for neurologists in practice and training.

Contributors viiSeries Foreword xPreface xichapter 1 1EtiologySonya U. Steele and Ellen M. Mowrychapter 2 10Immunopathogenesis of Multiple SclerosisAnne H. Cross and Laura Picciochapter 3 18Diagnostic ProcessDalia Rotstein and Paul O'Connorchapter 4 29MRI in Diagnosis and Disease MonitoringMaría I. Gaitán and Daniel S. Reichchapter 5 45Relapsing MS: Disease Staging and Therapeutic AlgorithmsMohsen Khoshnam and Mark Freedmanchapter 6 57Progressive MS Treatment AlgorithmsMegan H. Hyland and Jeffrey A. Cohenchapter 7 67Sex-Determined Issues in Multiple SclerosisCallene Momtazee and Barbara Giesserchapter 8 77Pediatric Multiple SclerosisRobert Thompson Stone and Brenda Banwellchapter 9 91Complementary and Alternative Medicine: Risks and BenefitsAllen C. Bowlingchapter 10 102Symptomatic Management of MSJessica Robb, Lawrence M. Samkoff, and Andrew D. Goodmanchapter 11 114Invisible Symptoms of MS: Fatigue, Depression, and CognitionLeigh E. Charvet, Benzi Kluzer, and Lauren B. Kruppchapter 12 122RehabilitationNesanet S. Mitiku, Alexius E. G. Sandoval, and George H. Kraftchapter 13 134Psychosocial Adaptation to Multiple SclerosisDavid J. Rintellchapter 14 144Transverse Myelitis and Acute Disseminated EncephalomyelitisBenjamin M. Greenbergchapter 15 153Neuromyelitis OpticaMarcelo Matiello and Brian G. Weinshenkerchapter 16 163NeurosarcoidosisThomas F. Scottchapter 17 169Lyme NeuroborreliosisErica Patrick and Eric Logigianchapter 18 178Neuro-Behçet SyndromeAksel Siva and Sabahattin SaipIndex 191