This book summarizes rapid progress and innovation in transplantation and regenerative medicine - the merger of reconstructive plastic surgery and transplantation - called Vascularized Composite Allotransplantation. This merger includes a wide variety of previously impossible translplantations using grafts derived from organ donors.

Contributors. CELLULAR THERAPIES IN RECONSTRUCTIVE TRANSPLANTATION. Cell Therapies in Reconstructive Transplantation. Novel T-Regulatory Cell-Based Therapies in Vascularized Composite Allotransplantation: Translational Implications. UNIQUE CONSIDERATIONS AND EMERGING INDICATIONS IN RECONSTRUCTIVE TRANSPLANTATION. Invasive and Non-Invasive Surrogates for Chronic Rejection in Vascularized Composite Allotransplantation: Claims and Controversies. Reperfusion Injury in Vascularized Composite Tissue Allografts: Impact on Graft Outcomes and Preventive Strategies. Pediatric Upper Extremity Vascularized Composite Allotransplantation: Progress and Insights. GRAFT MONITORING IN RECONSTRUCTIVE TRANSPLANTATION. Targeted Imaging and Therapeutic Technologies in Neuroregeneration. Biomarkers and Surrogates of Acute Rejection in Vascularized Composite Allograft Transplantation. COMPOSITE TISSUE GRAFT MANIPULATION AND ENGINEERING. Bioengineering Composite Tissue Constructs: Concepts and Challenges. Advances in Biomaterials for Reconstructive Transplantation. Gene Editing Strategies for Immunomodulation: Translation from Cells to Vascularized Tissues. Index.