Edhf 2000
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ISBN-13:
9780415269049
Veröffentl:
2001
Erscheinungsdatum:
29.11.2001
Seiten:
544
Autor:
Paul M Vanhoutte
Gewicht:
1175 g
Format:
257x173x29 mm
Sprache:
Englisch
Beschreibung:
Understanding the nature and role of endothelium-derived hyperpolarizing factor is crucial in the quest for improved treatments for hypertension, diabetes, ischemia-reperfusion, and other vascular disorders. The book focus on the role of gap junctions in cardiovascular responses and investigate the chemical identity of EDHF. EDHF 2000 will be of interest not only to physiologists and pharmacologists puzzled by the complexity of the interactions between the endothelium and underlying vascular smooth muscle cells, but also clinical researchers and physicians treating patients with cardiovascular diseases.
1. What do gap junctions do anyway? 2. Cardiovascular gap junctions: Functional Diversity, complementation and specialization of connexins 3. Endothelium and smooth muscle pathways for conduction along resistance microvessels 4. Membrane potential and calcium responses evoked by acetylcholine in submucosal arterioles of the guinea-pig small intestine 5. The effects of ouabain, 18a-glycyrrhetinic acid and connexin-mimetic peptides on intercellular communication in cells expressing a
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