Molecular Chaperones

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Part One: Chaperones for genome replication and expression. Introduction: the molecular chaperone concept - R J Ellis. Neucleoplasmin and modulations of chromatin structure - R A Laskey. Microbial DNA replication - M Zylicz. The control of gene expression - S Lindquist. Part Two: Chaperones for protein folding. Protein in self-assembly - R Jaenicke. Interactions of chaperonins with folding intermediates - G H Lorimer. Chaperonin-mediated protein folding at high temperatures - M Yoshida. Chaperonin-like proteins in archaebacteria - A Horwich. Chaperones and nascent polypeptides - W J Welch. Tumour suppressor gene products as chaperones - D P Lane. Part Three: Chaperones for protein transport. Introduction - A Coleman. Microsomal protein transport - J E Rothman. Transport and assembly processes in the endoplasmic reticulum - M J Gething. Bacterial protein transport S J S Hardy. Mitochondrial protein transport - W Neupert. Part Four: Chaperones and disease. Chaperonins and the immune response - D B Young.
Currently one of the hottest topics in biochemistry, the concept of molecular chaperones has challenged the paradigm of protein self-assembly. Key figures in many disciplines review all aspects of molecular chaperones in this volume, which arises from a Royal Society discussion meeting. Overview chapters discuss the significance of chaperones in biochemistry, molecular genetics and cell biology. Each chapter is well referenced providing access to the literature.

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Autor: R. J. Ellis
ISBN-13 :: 9780412550607
ISBN: 0412550601
Erscheinungsjahr: 30.09.1993
Verlag: Springer Netherlands
Gewicht: 588g
Seiten: 136
Sprache: Englisch
Auflage 1993
Sonstiges: Buch, 297x210x13 mm
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