Genomics of Disease

"The title will develop from the 24th Stadler symposium. It will explore the general theme "GENOME EXPLOITATION: Data Mining the Genomes". The idea behind the theme is to discuss and illustrate how scientists are going to characterize and make use of the massive amount of information being accumulated about plant and animal genomes. The book will present a state-of-the-art picture on mining the Genome databases. This will be one of the few times that researchers in both plants and animals will be working together to create a seminal data resource. TOC:Signaling networks in plant defense.- Genetic Mapping of Complex.- Genomics of the rice defense signaling pathway.- Genetic interactions that mediate autoimmune disease.- Extracting meaning from high-dimensional 'omics data.- Unraveling the genetic mysteries of the Cat: New discoveries in feline inherited diseases and traits.- Variation in chicken gene structure and expression associated with food-safety pathogen resistance.- Functional Genomics and Bioinformatics of the Soybean-Phytophthora Interaction.- The genetics governing merle coat patterning in the domestic dog and association of merle with auditory and ophthalmologic abnormalities.- Associating genomic variation of diverse rice varieties to understand disease resistance.- AKT1 haplotypes control bone and muscle volumes, fasting serum glucose, and risk for metabolic syndrome.- Ovine disease resistance-integrating comparative and functional genomics approaches in a genome information-poor species.- Finding the Achilles heel in virus replication and strategies that can limit disease in transgenic crops.- Integrating genomics to understand the Marek's disease virus chicken host-pathogen interaction.- Comparative genomics of virulent Pseudomonas aeruginosa isolates.- Genetic dissection of the interaction between the plant pathogen Xanthomonas and its host plants.- Landscape of comparative genomics in mammals.- Reprogramming the host: The effector secretome of Phytophthora.- New insights into biotrophic development of Ustilago maydis.- Evolution of virulence in malaria.- The ins and outs of host recognition of Magnaporthe grisea.- Epidermal growth factor receptor: pleiotropic effects associated with extensive genetic heterogeneity.- A high-performance custom microarray for phenotypic analysis of plant defense signaling mutants.- Massively parallel eQTL analysis of complex traits in mice."

Roles of Plant Hormones in Plant Resistance and Susceptibility to Pathogens.- Canine Genetics Facilitates Understanding of Human Biology.- Xanthomonas oryzae pv. oryzae AvrXA21 Activity Is Dependent on a Type One Secretion System, Is Regulated by a Two-Component Regulatory System that Responds to Cell Population Density, and Is Conserved in Other Xanthomonas spp..- Unraveling the Genetic Mysteries of the Cat: New Discoveries in Feline-Inherited Diseases and Traits.- Variation in Chicken Gene Structure and Expression Associated with Food-Safety Pathogen Resistance: Integrated Approaches to Salmonella Resistance.- Functional Genomics and Bioinformatics of the Phytophthora sojae Soybean Interaction.- Canine SINEs and Their Effects on Phenotypes of the Domestic Dog.- Ovine Disease Resistance: Integrating Comparative and Functional Genomics Approaches in a Genome Information-Poor Species.- Integrating Genomics to Understand the Marek's Disease Virus - Chicken Host-Pathogen Interaction.- Combining Genomic Tools to Dissect Multifactorial Virulence in Pseudomonas aeruginosa.- Genetic Dissection of the Interaction Between the Plant Pathogen Xanthomonas campestris pv. vesicatoria and Its Host Plants.- Structure and Function of RXLR Effectors of Plant Pathogenic Oomycetes.- The Biotrophic Phase of Ustilago maydis: Novel Determinants for Compatibility.- Virulence Evolution in Malaria.- The Ins and Outs of Host Recognition of Magnaporthe oryzae.