The high demand for brain PET scans in dementia and related disorders is driven by both the prevalence of these conditions and the difficulty of distinguishing the causes of cognitive impairment. The clinical utility of brain PET in such cases depends in part on how accurately and fully the information inherently represented in a scan is appreciated and relayed in the interpretation of the images. Since this can be challenging for even the most highly trained imaging specialists, PET in the Evaluation of Alzheimer's Disease and Related Disorders takes a ground-up look at PET as it relates to the evaluation of patients with cognitive impairment. Expert contributors weigh in on when and why to order brain PET scans, their clinical interpretation, FDG PET in the evaluation of mild cognitive impairment and early dementia, PET and SPECT for central motor disorders, microstructural imaging of neurodegenerative changes, and amyloid imaging. The book is illustrated throughout with color images and also includes an interpretive practice atlas for self-testing of skills.

"This practical guide contains all the science and clinical information needed to help the reader make informed decisions about the applications of brain PET to improve the care of patients with symptoms of Alzheimer's disease and related disorders. Beginning with an introduction to goals and limitations of the clinical evaluation of dementia, Dr. Dan Silverman and his distinguished group of contributors cover the role of functional imaging, clinical interpretation of brain FDG-PET scans, FDG-PET in the evaluation of early dementia, microstructural imaging of neurodegenerative changes, amyloid imaging, imaging non-neurodegenerative causes of cognitive impairment, tools for assisting PET scan interpretation in the clinical setting, and PET evaluation of central motor disorders. There is also a complete collection of clinical cases that practitioners are likely to encounter in daily practice. Enhanced with numerous PET brain scans, this book fills a rapidly growing need in the medical imaging field."

Imaging Applications in Current Clinical Practice.- Clinical Evaluation of Dementia and When to Perform PET.- Clinical Interpretation of Brain PET Scans: Performing Visual Assessments, Providing Quantifying Data, and Generating Integrated Reports.- FDG PET in the Evaluation of Mild Cognitive Impairment and Early Dementia.- PET and SPECT in the Evaluation of Patients with Central Motor Disorders.- Emerging Approaches Using PET.- Microstructural Imaging of Neurodegenerative Changes.- Amyloid Imaging with PET in Alzheimer's Disease, Mild Cognitive Impairment, and Clinically Unimpaired Subjects.- Atlas.- Interpretive Practice Atlas.