The past decade has brought great advances in our understanding of the mechanisms underlying auditory pathologies. Molecular biology and genetics have primarily contributed to this enhanced understanding, which in turn has driven the design of novel rational therapeutic interventions. Auditory Trauma, Protection and Repair presents recent developments in auditory research and their potential translation to the clinical setting. In particular the authors address the major entities of peripheral auditory trauma, discuss the underlying mechanisms, the central nervous system consequences, protective interventions and finally explore the possibilities to restore cochlear morphology and function.

"The past decade has brought great advances in our understanding of the mechanisms underlying auditory pathologies. Molecular biology and genetics have primarily contributed to this enhanced understanding, which in turn has driven the design of novel rational therapeutic interventions. This volume presents recent developments in research and their potential translation to the clinical setting. The volume addresses the major entities of peripheral auditory trauma, discusses the underlying mechanisms, the central nervous system consequences, protective interventions and finally explores the possibilities to restore cochlear morphology and function. TOC:Introduction.- Genetics of Hearing Loss.- Noise-Induced Hearing Loss.- Drug-Induced Hearing Loss. Age-Related Hearing Loss.- Protecting The Inner Ear.- Central Consequences of Cochlear Trauma.- Tinnitus.- Homeostatic Disorders and Meniere's Disease.- Autoimmune Hearing Loss.- Restoring The Cochlea.- Prospects For Stem Cell Therapy."

Auditory Pathology: When Hearing is Out of Balance.- Genetics of Hearing Loss.- Cochlear Homeostasis and Homeostatic Disorders.- Tinnitus: Theories Mechanisms and Treatments.- Autoimmune Inner Ear Disease.- Age-Related Hearing Loss and Its Cellular and Molecular Bases.- Patterns and Mechanisms of Noise-Induced Cochlear Pathology.- Drug-Induced Hearing Loss.- Central Consequences of Cochlear Trauma.- Cell Death and Cochlear Protection.- Emerging Strategies for Restoring the Cochlea.