Beschreibung:
This book present in novel, distinct, but highly related aspects of the intracellular mechanisms required for the formation of a functional neurite, which include cytoskeletal organization, membrane traffic, and signal transduction. Its aim is to present this topic to the general readership of neurobiologists and molecular and cellular biologists to further stimulate the interest into this exciting section of neurobiology.
Presents novel, distinct, but highly related aspects of the intracellular mechanisms required for the formation of a functional neurite, which include cytoskeletal organization, membrane traffic, and signal transduction
Adhesion-Induced Intracellular Mechanisms of Neurite Elongation.- Regulation of Growth Cone Initiation and Actin Dynamics by ADF/Cofilin.- Role of Microtubules and MAPs During Neuritogenesis.- Small GTPases: Mechanisms Linking Membrane Traffic to Cytoskeleton During Neuritogenesis.- Exocytic Mechanisms for Axonal and Dendritic Growth.- Role of the Golgi Apparatus During Axon Formation.- Focal Adhesion Kinase in Neuritogenesis.- Regulation of Neuronal Morphogenesis by Abl Family Kinases.- Membrane Glycolipids in Neurotrophin Receptor-Mediated Signaling.- Wnt Signaling in Neurite Development.- Role of CRMP-2 in Neuronal Polarization.- Regulation of Axon Branching.- Comparative Analysis of Neural Crest Cell and Axonal Growth Cone Dynamics and Behavior.- Mechanisms of Axon Regeneration.