Beschreibung:
Statistical Monitoring of Clinical Trials: Fundamentals for Investigators introduces the investigator and statistician to monitoring procedures in clinical research. Clearly presenting the necessary background with limited use of mathematics, this book increases the knowledge, experience, and intuition of investigations in the use of these important procedures now required by the many clinical research efforts.
"Statistical Monitoring of Clinical Trials: Fundamentals for Investigators introduces the investigator and statistician to monitoring procedures in clinical research. Clearly presenting the necessary background with limited use of mathematics, this book increases the knowledge, experience, and intuition of investigations in the use of these important procedures now required by the many clinical research efforts.
Here, There be dragons....- The Basis of Statistical Reasoning in Medicine.- Probability Tools for Monitoring Rules.- Issues and Intuition in Path Analysis.- Group Sequential Analysis Procedures.- Looking Forward: Conditional Power.- Safety and Futility.- Bayesian Statistical Monitoring.