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Cytokines and Cancer

 eBook
Sofort lieferbar | Lieferzeit: Sofort lieferbar I
ISBN-13:
9780387243610
Einband:
eBook
Seiten:
378
Autor:
Leonidas C. Platanias
Serie:
126, Springer Cancer Treatment and Research
eBook Typ:
PDF
eBook Format:
EPUB
Kopierschutz:
1 - PDF Watermark
Sprache:
Englisch
Beschreibung:

The first book to cover both basic science and clinical research, providing a comprehensive review of the current knowledge on cytokines and cancer. Written by leading figures in the field of cytokine biology and cytokine therapeutics.
"This book is a comprehensive review of the current knowledge on cytokines and cancer. Cytokines play a variety of roles in cancer, both as components of pathogenetic mechanisms, as well as agents used in the treatment of certain malignancies. To date, there has not been a book that covers both basic science and translational/clinical research in the field of cytokines in malignancies. This book is written by leading figures in the field of cytokine biology and cytokine therapeutics and is specifically focused on this subject. The book is divided into two parts. The first part is focused on current developments in the basic science field. There is a particular emphasis on novel mechanisms of cytokine actions in malignant cells. The second part deals with translational and clinical research in the field, and many of the authors of these chapters were among the first to introduce several cytokines in the treatment of certain tumors.
Polypeptide Growth Factors and Their Receptors.- Chemokines and Cancer.- Interferons.- Cytokines and Lymphomas.- Proapototic and Antiapoptoitic effects of Tumor Necrosis Factor in Tumor Cells.- Transforming Growth Factor Beta and Breast Cancer.- Transforming Growth Factor Beta in Prostate Cancer.- Angiostatin.- Clinical and Translational Research.- Interferons in the Treatment of Solid Tumors.- Targeting Cytokine Receptors and Pathways in the Treatment of Breast Cancer.- Interleukin-2 in the Treatment of Renal Cell Carcinoma and Malignant Melanoma.- Cytokine Targeted Treatments for Lung Cancer.- Cytokines in the Treatment of Acute Leukemias.- Cytokines in Hematopoietic Stem Cell Transplantation.- Novel Cytokines in the Treatment of Malignancies.- Index.

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