Beschreibung:
In all organs of the body proteases have critical roles to play both in normal development and functioning and in disease states. The brain is no exception to this, with proteases having emerging roles in synaptic plasticity, memory, neurodegenerative disorders such as Alzheimer's, Parkinson's and prion diseases, ischemia and traumatic brain injury, inflammatory and infectious diseases, and tumour progression. Proteases in the Brain brings together a wide range of topics under this central theme and highlights the large number of proteases involved in these normal and disease processes.
Of interest for both advanced researchers/neurologists as well as for students of biology and medicine
Proteases and Alzheimer's Disease: Present Knowledge and Emerging Concepts of Therapy.- Calpain Proteolysis and the Etiology of Parkinson's Disease: An Emerging Hypothesis.- Cysteine Proteases in Neuronal Death in Brain Ischemia.- Proteases in Traumatic Brain Injury.- Proteases in CNS Infection and Inflammation.- Dipeptidyl Peptidase IV Regulates T Cell Function in CNS Inflammation.- Role and Regulation of Proteases in Human Glioma.- Proteases and Prion Diseases.- Neuropeptide Processing.- Proteases and Neuronal Plasticity.- Serine Proteases and Neuronal Plasticity in vivo.- Proteases and Synaptic Activity.- Role of Proteinase-Activated Receptors in Brain Function.- Matrix Metalloproteinases and Neuroinflammation in Multiple Sclerosis.