Beschreibung:
The main purpose of Genomic and Computational Tools for Infectious Diseases is to systematically present to the reader with a description and review of the principles, methodology, applications, and challenges related with the use of genomic tools to study influenza, HIV, encephalic and hemorrhagic viruses, malaria, and tuberculosis. This book will compile a comprehensive overview of the application of computational technologies to understand the biocomplexity of new and reemerging infectious diseases. The intent of this book is not to exhaustively survey the published literature on microbial functional genomics or bioinformatic tools, but rather, to provide the reader with representative examples and an illustrative guide of basic principles, approaches, and applications in genomics and computational biology specifically applied to specific pathogens.
review of the principles, methodology, applications, and challenges related with the use of genomic tools to study influenza, HIV, encephalic and hemorrhagic viruses, malaria, and tuberculosis.
The Economical Burden of Infectious Diseases.- Evolution Comparative Evolutionary Genomics of the MHC.- Quantitative Analysis and Modeling of the MHC.- Genomics and Evolution of Influenza.- RNAi Therapeutics for viral Diseases.- Computational Methods for Barcoding Viral Species.- Structural Analysis of Viral Proteins.- Genomic Analysis of Dengue Attenuated Vaccines.- Genomic Analysis of Viral-Host Interactions.- Functional Genomics of Malaria.- Systems Biology for the Rational Development of Antimalarials.- Constructing Tuberculosis Molecular Pathways.- Diagnostic of Emerging Viral and Bacterial Pathogens.- Mathematical Modeling of Early Detection of Infectious Disease Outbreaks.