Beschreibung:
Discusses integral, pragmatic approach to solving problems relevant to biostatistics function in the pharmaceutical industry, emphasizes importance of logical, systematic thinking, clear problem formulation and answering research questions in selected terms.
Answers to Inevitable Questions. A Road to an Integral Approach: Atlas and Caryatid of Biostatistics. Atlas-Statistical Programming. Caryatid-Data Management. Further Down the Road: Where and How We Live-Tactical Aspects. Environment: Biostatistics in the Regulatory Science Setting. Toolkit: Pharmacometrics. Broadening the View: Making Life Interesting-Strategic Aspects. Environment Enhancement: Teaching Statistical Concepts to Medical Colleagues. Where Should We Go?-Portfolio Optimization- and How Can We Do It Faster?-Adaptive Clinical Development Strategies. What Are We Measuring? And How Should We Do This?-Development of New Validated Scoring Systems. Can We Survive Mistakes?-Resurrecting a Failed Clinical Program. Can We Predict Unpredictable?-Planning the Timelines of Real-Life Open-Ended Projects.