The Cause of Pyloric Stenosis of Infancy chronicles the debate surrounding the cause of pyloric stenosis from its earliest discovery 300 years ago to the present. The Primary Hyperacidity Theory offers a credible explanation for all the classical signs and symptoms of pyloric stenosis as well a its associated features. In addition, this book comprehensively explores the medical and surgical treatment options as well as the general features used for diagnosis. An understanding of the true cause of pyloric stenosis will thus allow for treatment that is more individualized and sensitive to patients' needs.

1. The early descriptions2. The early theories of causation3. History of medical treatment4. Early surgical treatment5. Ramstedt and beyond6. The alkalosis story7. The personal story8. What makes the adult pyloric sphincter contract?9. How does acid in the duodenum trigger sphincter contraction?10. Stomach motility and gastric emptying11. The pyloric sphincter and pyloric stenosis of infancy12. Symptoms-signs and other clues13. Genetics-the seed and the soil14. The gastrin connection-- is it responsible for neonatal hyperacidity?15. The hesitant beginnings of the primary hyperacidity theory of cause16. The primary hyperacidity theory17. Clinical aspects and their explanation18. The link between pyloric stenosis of infancy and duodenal ulcer in adults: feedback --negative and positive19. Other contemporary lines of enquiry20. Conclusion21. The PS or reflux dilemma: Addendum 1 22. The real world: Addendum 2