The Handbook of Fungal Biotechnology offers the newest developments from the frontiers of fungal biochemical and molecular processes and industrial and semi-industrial applications of fungi. This Second Edition highlights the need for the integration of a number of scientific disciplines and technologies in modern fungal biotechnology and reigns as the top source on current molecular, biochemical, and medical technologies and commercial usages for fungi. Authored by 81 world-renowned scientists from both industry and academia, it addresses contemporary issues pertaining to intellectual property rights, biodiversity, and biosafety, and devotes an entire section to medical biotechnology.

CELL BIOLOGY, BIOCHEMICAL AND MOLECULAR TECHNOLOGIES. Cell Biology of Hyphae. Protoplast Isolation,Regeneration,and Fusion in Filamentous Fungi. Metabolic Pathway Regulation. Fungal Nuclei and Chromosomes. Genomics of Filamentous Fungi: A General Review. Stability and Instability of Fungal Genomes. Secondary Metabolic Gene Clusters in Filamentous Fungi. Application of Gene Cloning in Fungal Biotechnology. Transformation and Gene Manipulation in Filamentous Fungi: An Overview. Genetic Manipulation Systems for Nonconventional Fungi. Fungal Mitochondria: Genomes, Genetic Elements, and Gene Expression. Fungal Evolution Meets Fungal Genomics. Genome Sequence Patterns and Gene Regulation: A Bioinformatics Perspective. DNA Chips and Microarray Analysis: An Overview. Signal Transduction in Fungi: Signaling Cascades Regulating Virulence in Filamentous Fungi. COMMERCIAL APPLICATIONS AND BIOTECHNOLOGICAL POTENTIAL. Application of Genetic Engineering for Strain Improvement in Filamentous Fungi. The Genetic Improvement of Wine Yeasts. Fungi in Brewing: Biodiversity and Biotechnology Perspectives. Ethanol-Tolerance and Production by Yeast. Solid-State Fermentation: An Overview. Basic Principles for the Production of Fungal Enzymes by Solid-State Fermentation. Commercial Importance of Some Fungal Enzymes. Xylanases of Thermophilic Molds and Their Application Potential. Chitin Biosynthesis in Fungi. Bioactive Fungal Polysaccharides and Polysaccharopeptides. Biotechnological Potential of Fungal Lipids. Introduction to the Theory of Metabolic Modeling and Optimization of Biochemical Systems: Application to Citric Acid Production in Aspergillus niger. Fungal Carotenoid Production. Fungal Terpenoid Antibiotics and Enzyme Inhibitors. Commercial Production and Biosynthesis of Fungal Antibiotics: An Overview. Molecular Biology of Trichoderma and Biotechological Applications. Plectomycetes:Biotechnological Importance and Systematics. Exploitation of GFP-Technology with Filamentous Fungi. MEDICAL BIOTECHNOLOGY. Antifungal Drugs in Fungal Infections. Antitumor and Immunomodulatory Compounds from Fungi. Clinical and Laboratory Diagnosis of Fungal Infections. Candidiasis. Immunizations Against Fungal Diseases in Man and Animals. CULTURE COLLECTIONS AND BIOSAFETY. Current Status of Fungal Collections and Their Role in Biotechnology. Benefits and Risks of Genetically Modified Foods: An Overview. Transgenic Mycoherbicides:Needs and Safety Considerations. Recent Developments in Biotechnology and Intellectual Property, Access to Genetic Resources, and Benefit-Sharing. Index.