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Alternative Toxicological Methods
ISBN-13:
9780203008799
Veröffentl:
2003
Seiten:
616
Autor:
Harry Salem
eBook Typ:
PDF
eBook Format:
EPUB
Kopierschutz:
2 - DRM Adobe
Sprache:
Englisch
Beschreibung:
Focusing on the science and not the politics, Alternative Toxicological Methods highlights the recent progress made in developing and validating replacement, reduction, and refinement alternatives to animal testing. The book concisely discusses the application of state-of-the-art methods such as genomics and proteomics to the toxicological sciences. It explores cutting-edge research on engineered tissue equivalents for screening ocular injury and on the utility of gene array technology in skin biology. This book will benefit toxicologists, cosmetic chemists, pharmacologists, experimental biologists, dermatologists, and ophthalmologists as well as regulatory officers.
Progress in the Validation and Regulatory Acceptance of Alternatives. Development and Predictive Methods Based on Mechanisms of Eye Irritation at the Ocular Surface. Dermal Testing Alternatives. A Case Study in the Use of Alternatives to Determine the Mechanism of Sulfur Mustard Action. Molecular Biomarkers, Transgenics and Imaging Techniques for Assessing Neurotoxicity. Role of Transgenics and Toxicogenomics in the Development of Alternative Toxicity Tests. Role of Imaging in the Development of Alternative Toxicity Tests. Recent Innovations in Alternatives.
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