Motor Neuron Disease in Adults reviews new information as it applies to all aspects of motor neuron disease (ALS, PLS, PMA). The choice of articles is for those that use evidence-based methods to ensure that the new information is solid and advances the topic or issue. The book can be used by anyone who provides any type of care to ALS patients. In particular, neurologists will find the latest information on diagnosis and management, as well as new information on genetics and frontotemporal lobe involvement. Allied health providers will find useful information for their discipline. Patients will also find both specific and general information to help understand what they are experiencing and how to help manage their symptoms.

Introduction to "Motor Neuron Disease"1. History of the Recognition of Motor Neuron Disease2. Nomenclature & Classification of Motor Neuron Disease3. Clinical Anatomy, Physiology and Pathology of Motor Neuron Disease4. Clinical Features of Motor Neuron Disease5. Frontotemporal Dysfunction and Dementia in Amyotrophic Lateral Sclerosis6. Laboratory Tests for Motor Neuron Disease7. Biomarkers for Motor Neuron Disease8. Imaging in Motor Neuron Disease9. Diagnostic Criteria for Motor Neuron Disease10. Differential Diagnosis of Motor Neuron Disease11. Progression of Motor Neuron Disease12. Epidemiology of Amyotrophic Lateral Sclerosis13. Genetics of Amyotrophic Lateral Sclerosis and Frontotemporal Dementia:14. Genome-wide Screening to Identify ALS-associated Genes:15. Pathology of ALS and Frontotemporal Lobar Degeneration:16. Convergence and Divergence in ALS Syndrome: Genetics, Molecular Pathways and Molecular Mechanisms:17. Immunologic Aspects of Amyotrophic Lateral Sclerosis:18. Cyanobacteria, ALS, and the BMAA Hypothesis19. Animal models of Adult Motor Neuron Disease20. Multidisciplinary Clinics and Practice Parameters/Guidelines21. Allied Health and Other Providers22. Respiratory Assessment and Management23. Nutritional Assessment and Management24. Communication Assessment and Management25. Psychological and Psychiatric Assessment and Management26. Symptoms and Management27. Intimacy, Sexuality and Pregnancy28. Quality of Life29. Caregiver Issues30. End of Life Care31. Costs of ALS Care:32. Clinical Trial Designs in ALS:33. Stem Cell Therapy for Motor Neuron Disease: