50 Studies Every Pediatrician Should Know presents key studies that have shaped the current clinical practice of pediatrics. Selected using a rigorous methodology, the studies cover topics including: allergy immunology, behavioral, cardiology, dermatology, endocrinology, ENT, general pediatrics, hematology, infectious disease, neonatology, nephrology, neurology, oncology, ophthalmology, orthopedics, and pulmonary. For each study, a concise summary is presented with an emphasis on the results and limitations of the study, and its implications for practice. An illustrative clinical case concludes each review, followed by brief information on other relevant studies. This is one of the only books of its kind to present a collection of the most influential clinical trials in pediatrics that are detailed enough to be used on rounds, but still easily digestible.

Section I: Allergy Immunology1. Efficacy of Immunoglobulin Plus Prednisolone in Prevention of Coronary Artery Abnormalities in Kawasaki DiseaseSection II: Behavioral2. Measles, Mumps, and Rubella Vaccination and Autism3. Treatment for adolescents with depression study (TADS)4. The Multimodal Treatment Study of Children with Attention Deficit/Hyperactivity Disorder (MTA)Section III: Cardiology5. Pharmacologic Closure of a Patent Ductus Arteriosus in Premature Infants6. The relation of overweight to cardiovascular risk factors among children and adolescents: the Bogalusa heart studySection IV: Dermatology7. Propranolol vs. Prednisolone for Symptomatic Proliferating Infantile Hemangiomas: A Randomized Clinical TrialSection V: Endocrinology8. Risk Factors for Cerebral Edema in Children with Diabetic KetoacidosisSection VI: ENT9. A Trial of Early Ear Tube Placement in Children with Persistent Otitis MediaSection VII: General Pediatrics10. Maintenance IV Fluid Requirements11. Predischarge Serum Bilirubin to Predict Significant Hyperbilirubinemia in Newborns12. Sudden Infant Death Syndrome Risk Factors: The Chicago Infant Mortality Study13. Treatment of Acute Otitis Media in Children14. The Human Papillomavirus Vaccine15. Evidence of Decrease in Vaccine-Type Human Papillomavirus (HPV) and Herd Protection in Adolescents and Young Women16. Effects of Lead Exposure in ChildhoodSection VIII: Hematology17. Iron Supplementation for Breastfed Infants18. Transfusion Strategies for Patients in Pediatric Intensive Care Units19. Prophylactic Penicillin in Sickle Cell AnemiaSection IX: Infectious Disease20. Empiric Antimicrobial Therapy for Skin and Soft-Tissue Infections21. Infants at Low Risk for Serious Bacterial Infection22. Outpatient Treatment of Febrile Infants at Low Risk for Serious Bacterial Infection23. Outpatient Treatment of Selected Febrile Infants Without Antibiotics24. Neonatal Fever Without a Source25. Serious Bacterial Infections and Viral Infections in Febrile Infants26. Chest Radiograph and Lower Respiratory Tract Infection27. Vidarabine Therapy of Neonatal Herpes Simplex Virus Infection28. Early Reversal of Pediatric and Neonatal Septic Shock29. Reduction of vertical transmission of human immunodeficiency virus (HIV)30. Palivizumab prophylaxis against Respiratory Syncytial Virus (RSV) in high risk infants31. The Spectrum of Bronchiolitis32. Preventing Early-Onset Neonatal Group B Streptococcal DiseaseSection X: Neonatology33. Apgar Scoring of Infants at Delivery34. Prophylactic Treatment with Human Surfactant in Extremely Preterm InfantsSection XI: Nephrology35. Oral versus Initial Intravenous Antibiotics for Urinary Tract Infection in Young Febrile Children36. Identifying children with minimal change disease (MCD)37. Chronic renal disease following poststreptococcal glomerulonephritisSection XII: Neurology38. Antipyretic Agents for Preventing Febrile Seizure Recurrence39. Febrile Seizures and Risk for Epilepsy40. Seizure Recurrence After First Unprovoked Afebrile Seizure41. Mortality and Childhood-Onset Epilepsy42. Identifying Children with Low-Risk Head Injuries Who Do Not Require Computed TomographySection XIII: Oncology43. Health-Related Quality of Life Among Children with Acute Lymphoblastic LeukemiaSection XIV: Ophthalmology44. Treatment of Acute Conjunctivitis in Children45. Screening for AmblyopiaSection XV: Orthopedics46. Differentiation Between Septic Arthritis and Transient Synovitis of the Hip in ChildrenSection XVI: Pulmonary47. Steroids for the Treatment of Croup48. Inhaled Corticosteroids for Mild Persistent Asthma49. Inhaled Salbutamol (Albuterol) vs. Injected Epinephrine in Acute Asthma50. Long-term Inhaled Hypertonic Saline for Cystic Fibrosis