A COMPLETE UPDATE AND REVISION OF THE CLASSIC TEXT"At last, a manual of operations for comparing the cost-effectiveness of a preventive service with a treatment intervention." --American Journal of Preventive MedicineTwenty years after the first edition of COST-EFFECTIVENESS IN HEALTH AND MEDICINE established the practical benchmark for cost-effectiveness analysis, this completely revised edition of the classic text provides an essential resource to a new generation of practitioners, students, researchers, and policymakers.Produced by the Second Panel on Cost-Effectiveness in Health and Medicine--a team of 13 experts from fields including decision science, economics, ethics, psychology, and medicine--this new edition is a comprehensive guide to the use of cost-effectiveness analysis as an evaluative tool at the institutional and policy levels. As health care systems face increasing pressure to derive maximum value from expenditures, the guidelines in this new text represent not just the best information available, but a vital guide to health care decision-making in a challenging new era.Completely revised and enriched with examples and expanded coverage, this second edition of COST-EFFECTIVENESS IN HEALTH AND MEDICINE builds on its predecessor's excellence, offering required reading for both analysts and decision makers.

ForewordAcknowledgmentsSecond Panel on Cost-Effectiveness in Health and MedicineFirst Panel on Cost-Effectiveness in Health and MedicineOverviewIntroduction1. Using Cost-Effectiveness Analysis in Health and Medicine: Experiences since the Original Panel2. Theoretical Foundations of Cost-Effectiveness Analysis in Health and Medicine3. Recommendations on Perspectives for the Reference Case4. Designing a Cost-Effectiveness Analysis5. Decision Models in Cost-Effectiveness Analysis6. Identifying and Quantifying the Consequences of Interventions7. Valuing Health Outcomes8. Estimating Costs and Valuations of Non-Health Benefits in Cost-Effectiveness Analysis9. Evidence Synthesis for Informing Cost-Effectiveness Analysis10. Discounting in Cost-Effectiveness Analysis11. Reflecting Uncertainty in Cost-Effectiveness Analysis12. Ethical and Distributive Considerations13. Reporting Cost-effectiveness AnalysesAppendix: Summary of Recommendations by ChapterWorked ExamplesOverview of Worked ExamplesWorked Example 1: The Cost-Effectiveness of Treatment for Individuals with Alcohol Use Disorders: A Reference Case AnalysisWorked Example 2: The Cost-Effectiveness of Home Palliative Care for Patients at the End of Life