Originally published in 1998, Psycho-Oncology was the first comprehensive text in the field and remains the gold standard today. Previously led by Dr. Jimmie C. Holland, the founder of the field, this new edition is edited by a team of internationally renowned experts in psycho-oncology. The text reflects the interdisciplinary nature and global reach of this growing field. It covers evidence-based clinical practice guidelines from around the world, survivorship issues, psychotherapeutic interventions, and psychopharmacologic interventions.Thoroughly updated and developed in collaboration with the American Psychosocial Oncology Society and the International Psycho-Oncology Society, the fourth edition is a current, comprehensive reference for psychiatrists, psychologists, oncologists, hospice workers, and social workers seeking to understand and manage the psychological issues involved in the care of persons with cancer and the psychological, social, and behavioral factors that contribute to cancer risk and survival.

Dedication: Jimmie C. Holland, MD (1928-2017)William S. BreitbartDedication: Ruth McCorkle, PhD, RN, FAAN (1941-2019)Mark LazenbyIntroduction: Our Past, Our Future: New Frontiers in Psycho-OncologyWilliam S. BreitbartSECTION I Behavioral and Psychological Factors in Cancer Risk and PreventionPaul B. Jacobsen (Section Editor)1 Tobacco Use and CessationThomas H. Brandon, Vani N. Simmons, Ursula Martinez, Patricia Calixte-Civil2 Diet and CancerMarian L. Fitzgibbon, Lisa Tussing-Humphreys, Angela Kong, Alexis Bains3 Physical Activity, Sedentary Behavior, and CancerChristine M. Friedenreich, Chelsea R. Stone, Jessica McNeil4 Sun Exposure and Cancer RiskSuzanne J. Dobbinson, Afaf Girgis, Bruce K. Armstrong, Anne E. Cust5 Psychosocial FactorsAnika von Heymann, Christoffer Johansen6 Viral Cancers and BehaviorSusan T. Vadaparampil, Lindsay N. Fuzzell, Shannon M. Christy, Monica L. Kasting, Julie Rathwell, Anna E. CoghillSECTION II Screening for Cancer in Normal and At-Risk PopulationsWendy W. T. Lam (Section Editor)7 Colorectal Cancer ScreeningCaitlin C. Murphy, Sally W. Vernon8 Cervical Cancer Screening and HPV Vaccination: Multi-level challenges to cervical cancer preventionRichard Fielding, Samara Perez, Zeev Rosberger, Ovidiu Tatar, Linda D. L. Wang9 Breast Cancer ScreeningGabriel M. Leung, Irene O. L. Wong, Ava Kwong, Joseph T. Wu10 Prostate Cancer ScreeningMichael A. Diefenbach, Daniel Nethala, Michael Schwartz, Simon J. Hall11 Lung Cancer ScreeningLisa Carter-Harris, Jamie Ostroff12 Skin Cancer ScreeningJennifer L. Hay, Stephanie N. ChristianSECTION III Screening and Testing for Germ Line and Somatic MutationsPaul B. Jacobsen (Section Editor)13 Psychosocial Issues in Genetic Testing for Breast/Ovarian CancerMary Jane Esplen, Jonathan Hunter, Eveline M. A. Bleiker14 Psychosocial Issues in Genetic Testing for Hereditary Colorectal CancerSukh Makhnoon, Susan K. Peterson15 Psychosocial Issues in Genomic Testing, Including Genomic Testing for Targeted TherapiesMegan Best16 Psychosocial Issues Related to Liquid Biopsy for ctDNA in Individuals at Normal and Elevated RiskJada G. Hamilton, Amanda Watsula-Morley, Alicia LathamSECTION IV Screening and Assessment in Psychosocial OncologyWendy W. T. Lam (Section Editor)17 Screening and Assessment for DistressAlex J. Mitchell18 Assessment, Screening, and Case Finding for Depression and Anxiety in People with CancerKristine A. Donovan, Paul B. Jacobsen19 Screening for Delirium and Dementia in the Cancer PatientChristian Bjerre-Real, James C. Root, Yesne Alici, Julia A. Kearney, William S. Breitbart20 Screening and Assessment for Cognitive ProblemsAlexandra M. Gaynor, James C. Root, Elizabeth Ryan, Tim A. AhlesSECTION V Psychological Issues Related to Site of CancerMark Lazenby (Section Editor)21 MelanomaNadine A. Kasparian, Iris Bartula22 Lung CancerMarianne Davies23 Breast CancerM. Tish Knobf, Youri Hwang24 Colorectal CancerAnne Miles, Claudia Redeker25 Prostate Cancer and Genitourinary MalignanciesAndrew J. Roth, Alejandro Gonzalez-Restrepo26 Pancreatic, Esophageal and Gastric, and Hepato-Biliary CancersDaniel C. McFarland, William S. Breitbart27 Gynecologic CancersHeidi S. Donovan, Teresa H. Thomas28 Hematopoietic Dyscrasias and Stem Cell Transplantation / CAR T Cell TherapyJesse R. Fann, Nicole Bates29 Head and Neck CancerLoreto Fern?ndez Gonz?lez, Jonathan Irish, Gary Rodin30 Central Nervous System TumorsAlan D. Valentine31 HIV Infection and AIDS-Associated NeoplasmsJoanna S. Dognin, Peter A. SelwynSECTION VI Management of Specific Physical SymptomsWilliam S. Breitbart (Section Editor)32 Cancer-Related PainR. Garrett Key, Dustin Liebling, Vivek T. Malhotra, Steven D. Passik, Natalie Moryl, William S. Breitbart33 Nausea and VomitingLaura J. Lundi, Kavitha Ramchandran34 Cancer-Related FatigueDaniel C. McFarland, Christian Bjerre-Real, Yesne Alici, William S. Breitbart35 Sexual Problems and CancerJeanne Carter, Ashley Arkema, Andrew J. Roth, Sally Saban, Christian J. Nelson36 Neuropsychological Impact of Cancer and Cancer TreatmentsAlexandra M. Gaynor, James C. Root, Tim A. Ahles37 Sleep and CancerAmy E. Lowery-Allison, Elizabeth Devon Eldridge-Smith38 Weight and Appetite Loss in CancerYesne Alici, Victoria Saltz39 Body Image-An Important Dimension in Cancer CareMary Jane Esplen, Michelle Cororve FingeretSECTION VII Psychiatric DisordersWilliam S. Breitbart (Section Editor)40 Adjustment Disorders in CancerFroukje de Vries, Sarah Hales, Gary Rodin, Madeline Li41 Depressive Disorders in CancerChristian Schulz-Quach, Madeline Li, Kim Miller, Gary Rodin42 Suicide and Medical Aid in DyingHayley Pessin, Elie Isenberg-Grzeda, William S. Breitbart, Reena Jaiswal, Monique James43 Anxiety DisordersAshley M. Nelson, Chelsea S. Rapoport, Lara Traeger, Joseph A. Greer44 DeliriumYesne Alici, William S. Breitbart45 Substance Use DisordersSameer Hassamal, Adam Rzetelny, and Steven D. Passik46 Post-traumatic Stress Disorder Associated with Cancer Diagnosis and TreatmentMatthew Doolittle, Katherine N. DuHamel47 Psychiatric Toxicities of Cancer Therapies: Focus on Immunotherapy and Targeted TherapyDaniel C. McFarland, Mehak Sharma, Yesne AliciSECTION VIII Evidence-Based InterventionsWilliam S. Breitbart and Phyllis N. Butow (Section Editors)Models of Care Delivery48 Delivering Integrated Psychosocial Oncology Care: The Collaborative Care ModelJesse R. Fann, Julia Ruark, Michael Sharpe49 The Engaged Patient: The Cancer Support Community's Comprehensive Model of Psychosocial Programs, Services, and ResearchMitch Golant, Alexandra K. Zaleta, Susan Ash-Lee, Joanne S. Buzaglo, Kevin Stein, M. Claire Saxton, Marcia Donziger, Kim Thiboldeaux, Linda Bohannon50 The Role of Implementation Science in Advancing Psychosocial CarePaul B. Jacobsen, Wynne F. NortonInterventions During Active Treatment51 Supportive Psychotherapy in CancerRosangela Caruso, Maria Giulia Nanni, Luigi Grassi52 Cognitive and Behavioral InterventionsBarbara L. Andersen, Nicole A. Arrato, Caroline S. Dorfman53 Meta-Cognitive ApproachesLouise Sharpe, Leah Curran54 Mindfulness-Based InterventionsLinda E. Carlson55 Acceptance and Commitment Therapy (ACT) for Cancer PatientsNicholas J. Hulbert-Williams, Ray Owen, Christian J. Nelson56 Supportive-Expressive and Other Forms of Group Psychotherapy in Cancer CareDavid W. Kissane57 Emotion-Focused TherapySharon Manne58 Interpersonal Psychotherapy and CancerJennifer Sotsky, Hayley Pessin, John C. Markowitz59 Integrative OncologySanthosshi Narayanan, Gabriel Lopez, Jun J. Mao, Wenli Liu, Lorenzo CohenInterventions for Families and Couples60 Psychosocial Interventions for Couples and Families Coping with CancerTalia I. Zaider, David W. KissaneInterventions for Advanced Cancer/End of Life/Bereavement61 Meaning-Centered PsychotherapyMelissa Masterson Duva, Wendy G. Lichtenthal, Allison J. Applebaum, William S. Breitbart62 Dignity TherapyHarvey Max Chochinov, Maia S. Kredentser63 Managing Cancer and Living Meaningfully (CALM) TherapySarah Hales, Gary Rodin64 Bereavement Interventions in the Setting of Cancer CareWendy G. Lichtenthal, Kailey E. Roberts, Holly G. Prigerson, David W. KissaneInterventions for Cancer Survivors65 Meaning-Centered Group Psychotherapy for Cancer SurvivorsNadia van der Spek, Wendy G. Lichtenthal, Karen Holtmaat, William S. Breitbart, Irma Verdonck-de Leeuw66 Physical Activity and Exercise Interventions in Cancer SurvivorsChloe Grimmett, Rebecca J. Beeken, Abigail FisherDigital Health Interventions67 e-Health Interventions for Cancer Prevention and ControlKelly M. Shaffer, Elliot J. Coups, Lee M. Ritterband68 Digital Health Interventions for Psychosocial Distress (Anxiety and Depression) in CancerLisa Beatty, Haryana Dhillon69 e-Health Interventions for Physical Symptom ControlBobby Robert Zachariae70 e-Health Interventions for Tobacco CessationChris Kotsen, Jamie Ostroff, Lisa Carter-HarrisSECTION IX Psychosocial Issues at the Time of DiagnosisMatthew J. Loscalzo (Section Editor)71 Treatment Decision MakingAllison Marziliano, Michael A. Diefenbach72 The Family Meeting: Communication across the Continuum of Cancer CareStefanie N. Mooney, Marinel OlivaresSECTION X Palliative and Supportive CareMark Lazenby (Section Editor)73 Psychological and Psychiatric Aspects of Palliative and End-of-Life Care: Synergies between Psycho-Oncology and Palliative CareScott A. Irwin, Nathan Fairman, Chase Samsel, Jeremy M. Hirst, Jason A. Webb, Manuel Trachsel74 Prognostic Understanding in Advanced Cancer PatientsLaura C. Polacek, Leah E. Walsh, Allison J. Applebaum, Barry RosenfeldSECTION XI Diversities in the Experience of CancerMatthew J. Loscalzo (Section Editor)75 Cancer, Culture, and Health DisparitiesMarjorie Kagawa-Singer, Annalyn Valdez-Dadia76 Financial Toxicity in Cancer TreatmentVictoria Blinder, Francesca M. Gany77 The Experience of Cancer as an ImmigrantFrancesca M. Gany, Jennifer Leng78 Sexual and Gender Minority Health in Psycho-OncologyCharles Kamen, Jennifer M. Jabson TreeSECTION XII Bio-Behavioral Psycho-OncologyWilliam S. Breitbart and Mark Lazenby (Section Editors)79 Psycho-Oncology, Stress Processes, and Cancer ProgressionMichael H. Antoni, Jennifer M. Knight, Susan K. Lutgendorf80 Depression, Inflammation, and CancerDaniel C. McFarland, Leah E. Walsh, Andrew H. Miller81 Biobehavioral Psycho-Oncology InterventionsMichael A. Hoyt, Frank J. PenedoSECTION XIII Geriatric Psycho-OncologyMatthew J. Loscalzo (Section Editor)82 The Older Cancer PatientBarbara A. Given, Charles W. Given83 Geriatric Psycho-Oncology Assessment Issues and InterventionsKelly M. Trevino, Rebecca M. Saracino, Andrew J. Roth, Yesne Alici, Christian J. Nelson84 Communicating with the Older Cancer PatientPatricia A. Parker, Smita C. Banerjee, Beatriz Korc-GrodzickiSECTION XIV Pediatric Psycho-OncologyWilliam S. Breitbart (Section Editor)85 Screening and Assessment in Pediatric Psycho-OncologyDarcy E. Burgers, Sarah J. Tarquini, Anne E. Kazak, Anna C. Muriel86 Psychiatric Disorders in Pediatric Psycho-Oncology: Diagnosis and ManagementJulia A. Kearney, Meredith E. MacGregor, Maryland Pao87 Evidence-Based Psychosocial Interventions in Pediatric Psycho-OncologyLori Wiener, Marie Barnett, Stacy Flowers, Cynthia Fair, Amanda Thompson88 Adolescent and Young Adult PatientsChristabel K. Cheung, Sheila J. Santacroce, Brad ZebrackSECTION XV Psychological Issues for the Family and CaregiversPhyllis N. Butow (Section Editor)89 Including Family Members in Caring for the Patient with Cancer: A Family-Centered ApproachDouglas S. Rait90 Couples Facing CancerHoda Badr, Courtney Bitz91 Cancer CaregiversAllison J. Applebaum, Erin Kent, Kristen Litzelman, Betty Ferrell, J. Nicholas Dionne-Odom, Laurel Northouse92 Addressing the Needs of Children When a Parent Has CancerCynthia W. Moore, Greer J. Dent, Paula K. RauchSECTION XVI SurvivorshipPhyllis N. Butow and Wendy W. T. Lam (Section Editors)93 Fear of Cancer RecurrenceAllan B. Smith, Joanna E. Fardell, Phyllis N. Butow94 Implementing the Survivorship Care Plan: A Strategy for Improving the Quality of Care for Cancer SurvivorsErin E. Hahn, Patricia A. Ganz95 Adult Survivors of Childhood CancerLisa A. Schwartz, Claire E. Wakefield, Jordana K. McLoone, Branlyn Werba DeRosa, Anne E. KazakSECTION XVII Building Supportive Care/Psycho-Oncology TeamsPhyllis N. Butow (Section Editor)Building Supportive Care Teams: Working Together and Self-Care96 Integrating Interdisciplinary Supportive Care Programs: Transforming the Culture of Cancer CareMatthew J. Loscalzo, Karen L. Clark, Barry D. Bultz, Juee Kotwal97 Occupational Stress in Oncology Staff: Burnout, Resilience, and InterventionsFay J. Hlubocky, Daniel C. McFarlandHealth Provider/Patient Communication98 Principles of Communication Skills Training in Cancer Care Across the Life Span and Illness TrajectoryDavid W. Kissane, Carma L. BylundSECTION XVIII Psycho-Oncology in Health PolicyWendy W. T. Lam (Section Editor)99 Distress, the Sixth Vital Sign: A Catalyst for Standardizing Psychosocial Care GloballyBarry D. Bultz, Matthew J. Loscalzo, Alex J. Mitchell, Jimmie C. Holland100 Implementation of Clinical Practice Guidelines for Psychosocial Cancer CareJane Turner, Nicole Rankin101 Emerging International Directions for Psychosocial Care: Perspectives from Asia and Low-Middle-Income CountriesJeff Dunn, Melissa Henry, Maggie WatsonIndex