Nuclear cardiac imaging refers to cardiac radiological diagnostic techniques performed with the aid of radiopharmaceuticals, which are perfused into the myocardium as markers. These imaging studies provide a wide range of information about the heart, including the contractility of the heart, the amount of blood supply to the heart and whether parts of the heart muscle are alive or dead. This is essential information for cardiologists, and nuclear imaging has become an increasingly important part of the cardiologist's armamentarium. Chapters in Nuclear Cardiac Imaging cover historical, technical and physiological considerations, diagnosis and prognosis, conditions other than Coronary Artery Disease (CAD), advanced cardiac imaging, and challenges and opportunities. New to the sixth edition are key point summaries at the start of each chapter, clinical cases with videos, and a question and answer chapter on practical issues. This volume is ideal for nuclear cardiologists in training and nuclear clinicians alike who are searching for quick answers to important clinical and technical questions.

Section I. Historical, Technical and Physiological Considerations1. Nuclear Cardiology: History and Milestones- Barry Zaret2. Radiation physics- James Galt3. SPECT and PET Instrumentation- James Galt and Ernest Garcia4. Kinetics of Conventional and New Cardiac Radiotracers- Ran Klein5. Radionuclide Angiography: Planar and Tomographic- Steven Port6. Gated SPECT MPI: Imaging Protocols and Acquisition; Processing and Quantitation- Milena Henzlova7. Image Artifacts- William Van DeckerSection II. Diagnosis and Risk Assessment8. Regulation of Myocardial Blood Flow: Henry Gewirtz9. How to measure Myocardial Blood Flow by PET?- Heinrich Schelbert10. How to measure Myocardial Blood flow by SPECT?- Terrence Ruddy11. Treadmill Exercise Testing- Gregory Thomas12. Pharmacological Stress Testing- Effie Andrikopoulou, Ami Iskandrian, Fadi Hage13. SPECT MPI in Diagnosis/Risk Assessment- Rami Doukky14. SPECT MPI for Risk Assessment in special groups (DM, Kidney transplant, Liver transplant, Asymptomatic, Obese)- Alberto Cuocolo15. SPECT MPI for Risk Assessment before non-cardiac surgery- Lawrence Phillips16. Evaluation of patients with Chest Pain in the Emergency Department- Jamieson Bourque17. Role of PET (Perfusion and MBF) in Diagnosis and Risk Assessment - Rob Beanlands18. Nuclear Imaging in women- Viviany Taqueti19. Myocardial Viability Assessment by Nuclear Techniques- Vasken DilsizianSection III. Role of Nuclear Imaging Beyond CAD20. Imaging dyssynchrony- Alessia Gimelli21. Imaging Myocardial Innervation by SPECT and PET- Mark Travin22. Imaging sarcoid heart disease- Paco Bravo23. Imaging Amyloid heart disease- Panithaya Chareonthaitawee24. Imaging infections of valves and devices- Thomas Schindler25. Imaging cardiac and vascular inflammation- Mehran Sadeghi and Sina Tavakoli26. Imaging in Heart Failure including those with devices and post cardiac transplant- Prem SomanSection IV. Advances in Nuclear Cardiac Imaging27. Evolving role of CT, cMR and echo in CAD- Jeroen BAx28. Hybrid Imaging: SPECT/CTA, PET/MR and SPECT Calcium Score: when and why?- Philipp Kaufmann and Ronny Buechel29. Artificial Intelligence and nuclear imaging- Piotr Slomka30. Nuclear Imaging in patients with serious arrhythmias- Saurabh Malhotra31. Nuclear Imaging in patients with HIV- Mouaz Al-Mallah32. Nuclear Imaging in cardio-oncology- Raymond Russell and Matt Harinstein33. Nuclear Imaging in patients with congenital heart diseases- Sharmila Dorbala and Sara PartingtonSection V. Challenges for Nuclear Cardiology34. Physician Certification and Lab Accreditation- Robert Hendel35. ACC/AHA/ESC Nuclear Guidelines and Appropriate Use Criteria- Timothy Christian36. Nuclear Cardiology Report generation- Wael Aljaroudi37. Radiation Considerations in imaging- Andrew J Einstein38. Statistics in Nuclear imaging- Charity Morgan39. Nuclear Imaging in Developing Countries- Amalia Peix and Diana PaezSection VI. Overview40. Ask the Experts- Ami E. Iskandrian, Fadi G. Hage, Pradeep Bhambhvani, Ernest V. GarciaAtlas Chapter 40: Self-Assessment