Vassopressin, Volume 111, the latest release in the Vitamins and Hormones series, first published in 1943, covers the field of hormone action, vitamin action, X-ray crystal structure, physiology and enzyme mechanisms, with this release focusing on topics relating to hepcidin, bacterial infection, and iron overload, the role of heparan sulfates in hepcidin regulation, hepcidin CDNA and human gene sex hormones, growth factors and hepcidin, HFE gene polymorphisms and hereditary hemochromatosis, hepcidin and il-1beta, hepcidin-ferroportin axis, cardiomyocyte hepcidin, adipocyte iron, leptin and hepcidin, regulators of hepcidin expression, and much more.

1. Evolution of proopiomelanocortin Ana Rocha, Alejandra Godino-Gimeno and José Miguel Cerdá-Reverter 2. Structure and dynamics of dynorphin peptide and its receptor Guillaume Ferré, Georges Czaplicki, Pascal Demange and Alain Milon 3. Molecular aspects of delta opioid receptors Louis Gendron, Karim Nagi, Manel Zeghal, Patrick M. Giguère and Graciela Pineyro 4. The role of heat shock protein 90 in regulating pain, opioid signaling, and opioid antinociception John M. Streicher 5. Enkephalinase regulation M. Ramírez-Sánchez, I. Prieto, A.B. Segarra, M. Martínez-Cañamero, I. Banegas and M. de Gasparo 6. Limbic circuit connectivity and the stress response: New insights into the mammalian nociceptin peptide system Allison Jane Fulford and Sarah Keskes 7. Enkephalins and ACTH in the mammalian nervous system Ewing Duque-Díaz, Olga Alvarez-Ojeda and Rafael Coveñas 8. Opioids and the hormone oxytocin Leda Kovatsi and Kakia Nikolaou 9. Estrogens as arbiters of sex-specific and reproductive cycle-dependent opioid mechanisms Alan R Gintzler, Emiliya M. Storman and Nai-Jiang Liu 10. Opioids and reproduction Beata Seeber, Bettina Böttcher, Elisabeth D¿Costa and Ludwig Wildt 11. Kappa opioid receptor and oligodendrocyte remyelination Fei Wang and Feng Mei 12. Inhibitory role of Gi-coupled receptors on cAMP-driven cancers with focus on opioid receptors in lung adenocarcinoma and its stem cells Hildegard M. Schuller 13. Prenatal ethanol exposure and enkephalinergic neurotransmission Milagros Méndez, Karla Hernández-Fonseca and Paula Abate