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Chemical Biology of the Genome
ISBN-13:
9780128176450
Veröffentl:
2021
Seiten:
350
Autor:
Siddhartha Roy
eBook Typ:
EPUB
eBook Format:
EPUB
Kopierschutz:
2 - DRM Adobe
Sprache:
Englisch
Beschreibung:
Chemical Biology of the Genome provides a comprehensive overview of essential concepts and principles of genomic and epigenomics dynamics as explored through the lens of chemical biology. Key examples and case studies illustrate chemical biology methods for study and analysis of the genome and epigenome, with an emphasis on relevance to physiological and pathophysiological processes and drug discovery. Authors and international leaders in biochemical studies of the genome, Drs. Siddhartha Roy and Tapas Kundu, adopt an integrated, interdisciplinary approach throughout, demonstrating how fast evolving chemical and mass-scale sequencing tools are increasingly used to interpret biochemical processes of the genome.
I. An integrative approach to chemical biology a) Philosophy behind the integrative approach b) Ensembles of molecules possess fundamentally different properties than individual molecules c) Physical tools for studying ensembles and their properties d) Chemical Genetics: A powerful approach to study cellular functions e) Genes and Genomes: An integral entity
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