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Epigenetics of Chronic Pain
ISBN-13:
9780128140710
Veröffentl:
2018
Seiten:
248
eBook Typ:
EPUB
eBook Format:
EPUB
Kopierschutz:
2 - DRM Adobe
Sprache:
Englisch
Beschreibung:
Epigenetics of Chronic Pain, Volume Nine, presents comprehensive information on the role of epigenetics in chronic pain sensitivity, providing a detailed, but accessible, view of the field from basic principles, to clinical application. Leading international researchers discuss essential mechanisms of chronic pain epigenetics, including the molecular processes of chromatin remodeling, histone modifications, and the microRNAs and noncoding RNAs involved in regulating genes tied to pain sensitivity. The influence of epigenetics in inflammatory, neuropathic, visceral and other pain models is examined, with data derived from epigenetic studies on peripheral and central mechanisms of pain sensitivity in animal models and clinical cases studies.
1. Epigenetic tools in chronic pain studies2. Epigenetic regulation of peripheral macrophages in neuropathic pain3. Emphasizing histone-related chromatin remodeling in the central nervous system of animal models of chronic pain4. Role of histone modifications in chronic pain development5. Role of DNA Methylation in Chronic Pain6. Pain-induced chromatin modifications7. DNA Methylation/Demethylation Homeostasis and Various Pain Conditions8. Epigenetic Modulation of Visceral Pain9. Non-coding RNAs are new players in chronic pain10. Epigenetics of Chronic Visceral Nociception11. An overview of epigenetic correlates of human chronic pain conditions
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