The Ovary, Third Edition, includes more than 60% new material that highlights the clinical aspects of human ovarian functions. It covers advances in the areas of genomics, assisted reproductive technology, and cancer diagnosis and treatment. This updated edition synthesizes new information at the molecular, cellular and organismal levels, while also presenting modern ovarian physiology in a more understandable and comparative context. The book looks at ovarian function from a detailed molecular and cellular level that examines all phases of the ovarian lifecycle that places special emphasis on the pathophysiology of the human ovary, including ovarian carcinogenesis.

Part I. The Ovarian Follicular Apparatus: Operational Characteristics1. Follicle Selection in Mammalian Ovaries2. Regulation of follicle formation and development by ovarian signaling pathway3. Human Folliculogenesis Revisited:  The Menstrual Cycle Visualized by Ultrasonography4. Development of the Mammalian Ovary and Follicles5. Organization of Ovarian Steroidogenic Cells and Cholesterol Metabolism 6. Inhibin, Activin and Follistatin in Ovarian Physiology7. Cell-cell Interactions in the Ovarian Follicles: Role of TGF-beta Superfamily Members8. Mutations and Polymorphisms, and their Functional Consequences, in Gonadotropin and Gonadotropin Receptor Genes 9. Environmentally Induced Epigenetic Transgenerational Inheritance of Ovarian DiseasePart II. Oocyte Maturation and Ovulation10. Mammalian Oogenesis - the fragile foundation of the next generation11. Regulation of Mammalian Oocyte Maturation12. Oocyte Meiotic Maturation13. Gene Expression During Oogenesis and Oocyte DevelopmentPart III. The Corpus Luteum15. Molecular Regulation of Progesterone Production in Corpus Luteum16. Corpus Luteum Formation 17. Luteolysis and The Corpus Luteum of PregnancyPart IV. Novel Experimental Models18. Transgenic Mouse Models in the Study of Ovarian Function 19. Genome-Wide Association Studies of Ovarian Function Disorders20. Mitchondria Research in Human Reproduction 21. The Role of Mitochondria in Reproductive Function and Assisted Reproduction Part V. Human Ovarian Pathophysiology: Select Aspects22. Ovarian Hyperstimulation Syndrome23. The Role of GnRH Agonist Triggering in GnRH Antagonist-Based Ovarian Stimulation Protocols24. The Ovarian Factor in Assisted Reproductive Technology25. The Role of Antimullerian Hormone in Assisted Reproduction 26. Polycystic Ovary Syndrome27. Genetic and Environmental Factors in the Aetiology of Polycystic Ovary Syndrome28. Germ Cell Failure and Ovarian Resistance: Human Genes and Disorders 29. Environmental Contaminants and Ovarian Toxicity 30. Autologous Transplantation of Human Ovarian Tissue 31. Oncofertility: Preservation of ovarian function after a cancer diagnosisPart VI. Human Ovarian Cancer32. Ovarian cancers: their varied origins and pathologically implicated microenvironment33. Phenotypic Plasticity and the Origins and Progression of Ovarian Cancer 34. Novel Therapeutic Approaches and Targets for Ovarian Cancer35. Molecular and Cellular Basis of Chemoresistance in Ovarian Cancer