Liquid Chromatography: Fundamentals and Instrumentation, Second Edition, is a single source of authoritative information on all aspects of the practice of modern liquid chromatography. It gives those working in both academia and industry the opportunity to learn, refresh, and deepen their understanding of new fundamentals and instrumentation techniques in the field.

1. Milestones in the development of liquid chromatography2. Kinetic theories of liquid chromatography3. Column technology in liquid chromatography4. Reversed-phase liquid chromatography5. Secondary chemical equilibria in reversed-phase liquid chromatography6. Hydrophilic interaction chromatography7. Hydrophobic interaction chromatography8. Liquid-solid chromatography9. Ion chromatography10. Size-exclusion chromatography11. Interaction polymer chromatography12. Affinity chromatography13. Solvent selection in liquid chromatography14. Method development in liquid chromatography15. Theory and practice of gradient elution liquid chromatography16. Comprehensive two-dimensional liquid chromatography17. General instrumentation in HPLC18. Advanced spectrometric detectors for identification and quantification: Mass spectrometry 19. Advanced IR and Raman detectors for identification and quantification20. Advanced spectrometric detectors for identification and quantification: Nuclear magnetic resonance21. Data analysis22. Validation of liquid chromatographic methods23. Quantitative structure property (retention) relationships in liquid chromatography24. Modeling of preparative liquid chromatography 25. Process concepts in preparative liquid chromatography 26. Miniaturization and microfluidics27. Nano-liquid chromatography28. Capillary electrochromatography29. Ultra-high performance liquid chromatography