The Practice of Medicinal Chemistry
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ISBN-13:
9780124172050
Veröffentl:
2015
Erscheinungsdatum:
30.09.2015
Seiten:
902
Autor:
Camille Georges Wermuth
Gewicht:
2642 g
Format:
284x217x50 mm
Sprache:
Englisch
Beschreibung:
The Practice of Medicinal Chemistry, Fourth Edition, provides a practical and comprehensive overview of the daily issues facing pharmaceutical researchers and chemists. In addition to its thorough and excellent treatment of basic medicinal chemistry principles, this updated edition has been thoroughly revised to provide new and expanded coverage of the latest technologies and approaches in drug discovery. . With in-depth coverage of high content screening, scoring, docking, binding free energy calculations, polypharmacology, QSAR, chemical collections and databases, and much more, this book is the go-to reference for all academic and pharmaceutical researchers who need a complete understanding of medicinal chemistry and its application to drug discovery and development.
Section 1 - General Aspects of Medicinal Chemistry Section 2 - Lead Compound Discovery Strategies Section 3 - Primary Exploration of Structure-Activity Relationships Section 4 - Substituents and Functions: Qualitative and Quantitative Aspects of Structure-Activity Relationships Section 5 - Spatial Organization, Receptor Mapping and Molecular Modeling Section 6 - Chemical Modifications Influencing the Pharmacokinetic Properties Section 7 - Pharmaceutical and Chemical Means to Solubility and Formulation Problems
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