Cell adhesion is a fundamental determinant of embryonic development and organogenesis. Cellular Adhesion in Development and Disease, volume 112 in Current Topics in Developmental Biology, comprehensively surveys current developments in understanding how adhesion systems affect organismal development. Topics covered include nectins, nectin-like molecules, and afadin in development; cadherin adhesion, signaling, and morphogenesis; endothelial cell junctions; epidermal development and barrier formation; and more.

1. How Adhesion forms the early Mammalian EmbryoMelanie D. White and Nicolas Plachta2. Regulation of Cell Adhesion and Cell Sorting at Embryonic BoundariesFrançois Fagotto3. Active Tension: The Role of Cadherin Adhesion and Signaling in Generating Junctional ContractilityRashmi Priya and Alpha S. Yap4. Integration of Cell-Cell Adhesion and Contractile Actomyosin Activity during MorphogenesisKatja Röper5. Nuclear Signaling from Cadherin Adhesion ComplexesPierre D. McCrea, Meghan T. Maher and Cara J. Gottardi6. Nectins and Nectin-Like Molecules in Development and DiseaseKenji Mandai, Yoshiyuki Rikitake, Masahiro Mori and Yoshimi Takai7. Anchors and Signals: The Diverse Roles of Integrins in DevelopmentAidan P. Maartens and Nicholas H. Brown8. Epithelial-Mesenchymal Transitions: From Cell Plasticity to Concept ElasticityPierre Savagner9. Embryonic Cell-Cell Adhesion: A Key Player in Collective Neural Crest MigrationElias H Barriga and Roberto Mayor10. VE-Cadherin in Vascular Development: A Coordinator of Cell Signaling and Tissue MorphogenesisAnne Karine Lagendijk and Benjamin M. Hogan11. Adhesion in Mammary Development: Novel Roles for E-Cadherin in Individual and Collective Cell MigrationEliah R. Shamir and Andrew J. Ewald12. Cell Adhesion in Epidermal Development and Barrier FormationKaelyn D. Sumigray and Terry Lechler13. Cadherin-Based Trans-Synaptic Networks in Establishing and Modifying Neural Connectivity Lauren G. Friedman, Deanna L. Benson and George W. Huntley14. Cell-Cell Interactions Driving Kidney MorphogenesisAlexander N. Combes, Jamie Davies and Melissa Little