Advances in Protein Chemistry and Structural Biology

Volume 79
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ISBN-13:
9780123812780
Veröffentl:
2010
Erscheinungsdatum:
28.07.2010
Seiten:
240
Autor:
Alexander Mcpherson
Gewicht:
544 g
Format:
231x155x18 mm
Sprache:
Englisch
Beschreibung:

Structural genomics is the systematic determination of 3-D structures of proteins representative of the range of protein structure and function found in nature. The goal is to build a body of structural information that will predict the structure and potential function for almost any protein from knowledge of its coding sequence. This is essential information for understanding the functioning of the human proteome, the ensemble of tens of thousands of proteins specified by the human genome.
1. Genomic studies and computational predictions of nucleosome positions and formation energiesAlexandre V. Morozov and Denis Tolkunov 2. Protein Homorepeats : Sequences, Structures, Evolution and FunctionsAndrey V. Kajava and Julien Jorda3. Protein Aggregation: from Inclusion Bodies to Amyloid and Biomaterials Anna Mitraki4. Taking charge of proteins: from neurodegeneration to industrial biotechnology Bryan F. Shaw , Demetri T. Moustakas , Julian P. Whitelegge , and Kym F. Faull 5. Histone Acetylation, Acetyltransferases, and Ataxia - Alteration of Histone Acetylation and Chromatin Dynamics is Implicated in the Pathogenesis of Polyglutamine Expansion Disorders Jean-Pol Vigneron and Priscilla SimonisShaun D. McCullough and Patrick Gran

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