Beschreibung:
The dark side of the genome represents vast domains of the genome that are not encoding for proteins - the basic bricks of cellular structure and metabolism. Up to 98% of the human genome is non-coding and produces so-called long non-coding RNA. Some of these non-coding RNA play fundamental roles in cellular identity, cell development and cancer progression. They are now widely studied in many organisms to understand their function.
1. Non-coding RNA, Its History and Discovery Timeline 2. Definition and Families of Long Non-coding RNA 3. Biological Functions of Long Non-coding RNA 4. Non-coding RNA in Development 5. Long Non-coding RNA and Cancer